Amitriptyline hydrochloride and Repaglinide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amitriptyline hydrochloride (amitriptyline hydrochloride) and Repaglinide (repaglinide). Common drug interactions include hyponatraemia among females and withdrawal syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Amitriptyline hydrochloride and Repaglinide. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Amitriptyline hydrochloride?

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.

What is Repaglinide?

Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.

On Jul, 26, 2026

27 people who take Amitriptyline hydrochloride and Repaglinide together, and have interactions are studied.

Amitriptyline hydrochloride and Repaglinide drug interactions.

What are the common drug interactions of Amitriptyline Hydrochloride and Repaglinide, by gender? *:

female:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Asthma
Drug ineffective
Hypersensitivity
Malaise (a feeling of general discomfort or uneasiness)
Pain
Pneumonia
Atrioventricular block (heart block)

male:

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Chronic kidney disease
Neoplasm malignant (cancer tumour)
Obesity (having too much body fat)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Dementia (madness)
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Amitriptyline Hydrochloride and Repaglinide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Maternal exposure during pregnancy (use of substance during pregnancy)

40-49:

Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Asthma
Drug ineffective

50-59:

n/a

60+:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Cardiac failure congestive
Constipation
Kidney infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neoplasm malignant (cancer tumour)
Obesity (having too much body fat)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Atrioventricular block (heart block)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 29.63%
Stress And Anxiety: 6 people, 22.22%
High Blood Pressure: 6 people, 22.22%
Pain: 3 people, 11.11%
Urinary Tract Infection: 2 people, 7.41%
Prostatic Adenoma (prostatic non-cancerous tumour): 2 people, 7.41%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 7.41%
Asthma: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Amitriptyline hydrochloride and Repaglinide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously