Amnesteem and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amnesteem (isotretinoin) and Effexor (venlafaxine hydrochloride). Common drug interactions include diarrhoea among females and affect lability among males.

The phase IV clinical study analyzes what interactions people have when they take Amnesteem and Effexor. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Amnesteem?

Amnesteem has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 7,344 Amnesteem users. Check the latest studies of Amnesteem.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.



On Jul, 19, 2026

13 people who take Amnesteem and Effexor together, and have interactions are studied.

Amnesteem and Effexor drug interactions.

What are the common drug interactions of Amnesteem and Effexor, by gender? *:

female:

  1. Diarrhoea
  2. Suicidal ideation
  3. Headache (pain in head)
  4. Abdominal pain
  5. Abnormal behaviour
  6. Abortion induced (medically referred abortion)
  7. Aggression
  8. Alanine aminotransferase increased
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Aspartate aminotransferase increased

male:

  1. Affect lability (emotional incontinence)
  2. Aggression
  3. Dry skin
  4. Groin pain
  5. Impulse-control disorder
  6. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  7. Psychotic disorder
  8. Suicidal ideation
  9. Blood triglycerides increased
  10. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)

What are the common drug interactions of Amnesteem and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Affect lability (emotional incontinence)
  2. Aggression
  3. Agitation (state of anxiety or nervous excitement)
  4. Anger
  5. Automatism (performance of actions without conscious thought or intention)
  6. Blood creatine phosphokinase increased
  7. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  8. Completed suicide (act of taking one's own life)
  9. Delirium (wild excitement)
  10. Discomfort

20-29:

  1. Headache (pain in head)
  2. Abortion induced (medically referred abortion)
  3. Drug exposure during pregnancy
  4. Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
  5. Suicide attempt

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Blood triglycerides increased
  3. Suicidal ideation
  4. Diarrhoea
  5. Abnormal behaviour
  6. Aggression

40-49:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Aspartate aminotransferase increased
  4. Diarrhoea
  5. Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
  6. Pyrexia (fever)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Dry Skin: 2 people, 15.38%
  2. Acne Cystic (skin problems that cause pimples): 2 people, 15.38%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Amnesteem and Effexor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amnesteem and Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amnesteem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amnesteem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin and venlafaxine hydrochloride (the active ingredients of Amnesteem and Effexor, respectively), and Amnesteem and Effexor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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