Amoxil and Naprosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxil (amoxicillin) and Naprosyn (naproxen). Common drug interactions include abdominal distension among females and cerebellar atrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxil and Naprosyn. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxil?

Amoxil has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 3,641 Amoxil users. Check the latest studies of Amoxil.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

On Jul, 16, 2026

37 people who take Amoxil and Naprosyn together, and have interactions are studied.

What are the common drug interactions of Amoxil and Naprosyn, by gender? *:

female:

Abdominal distension
Abdominal pain
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Arthropathy
Device dislocation
Dizziness
Dyspnoea (difficult or laboured respiration)
Emotional distress

male:

Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Chronic kidney disease
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Communication disorder (speech and language disorder)
Confusional state
Disturbance in attention
Dysthymic disorder (mild chronic depression disorder)
Gastroenteritis (inflammation of stomach and intestine)
Head injury

What are the common drug interactions of Amoxil and Naprosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain upper
Anxiety
Chest pain
Dyspnoea (difficult or laboured respiration)
Emotional distress
General physical health deterioration (weak health status)
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pleuritic pain

20-29:

Insomnia (sleeplessness)
Head injury
Loss of consciousness
Alcoholism (problems with alcohol)
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Dysthymic disorder (mild chronic depression disorder)
Gastroenteritis (inflammation of stomach and intestine)
Hepatitis c
Hypotension (abnormally low blood pressure)

30-39:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Rash scarlatiniform (rash 3-5mm size)
Skin exfoliation (removal of the oldest dead skin cells)
Vulval disorder
Pulmonary embolism (blockage of the main artery of the lung)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Emotional distress
Injury
Renal injury (kidney injury)
Renal tubular necrosis (death of kidney tubules)

40-49:

Dizziness
Dysarthria (speech disorder)
Emotional distress
Haemangioma of skin (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Hypoaesthesia (reduced sense of touch or sensation)
Injury
Memory impairment
Mood swings (an extreme or rapid change in mood)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)

50-59:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Chest discomfort
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Abdominal pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

60+:

Anaemia (lack of blood)
Abdominal pain
Cataract (clouding of the lens inside the eye)
Chest pain
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Colitis (inflammation of colon)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death

What are the existing conditions these people have? *

Depression: 6 people, 16.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.81%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 8.11%
Otitis Media (inflammation of the middle ear): 3 people, 8.11%
Migraine Without Aura (headache without neurological problems): 3 people, 8.11%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 8.11%
Toothaches (tooth pain): 2 people, 5.41%
Stress And Anxiety: 2 people, 5.41%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 5.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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