Amphotericin b and Sporanox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Amphotericin b (amphotericin b) and Sporanox (itraconazole). Common drug interactions include abortion spontaneous among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Amphotericin b and Sporanox. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.
What is Amphotericin b?
Amphotericin b has active ingredients of amphotericin b. It is often used in thrush. eHealthMe is studying from 16,275 Amphotericin b users. Check the latest studies of Amphotericin b.
What is Sporanox?
Sporanox has active ingredients of itraconazole. It is often used in fungal infection. eHealthMe is studying from 6,137 Sporanox users. Check the latest studies of Sporanox.
93 people who take Amphotericin b and Sporanox together, and have interactions are studied.

What are the common drug interactions of Amphotericin B and Sporanox, by gender? *:
female:
- Abortion spontaneous (naturally occurring miscarriage)
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Albuminuria present
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Aspartate aminotransferase increased
- Aspergillosis (an infection caused by a fungus called aspergillus)
- Blighted ovum
- Blood creatinine increased
- Blood lactate dehydrogenase increased
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
male:
- Drug ineffective
- Lung disorder (lung disease)
- Abdominal distension
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Weight decreased
- Chlamydial infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis)
- Epstein-barr virus infection
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Infection
- Infusion site infection
What are the common drug interactions of Amphotericin B and Sporanox, by age (0-1 to 60+)? *:
0-1:
- Mucosal inflammation (infection of mucous membrane)
- Neutropenia (an abnormally low number of neutrophils)
- Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
- Streptococcal bacteraemia (a bacterial infection of blood)
2-9:
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Pancreatitis acute (sudden inflammation of pancreas)
- Pyrexia (fever)
- Hepatitis (inflammation of the liver)
- Hepatocellular damage (liver damage)
- Infectious mononucleosis (infection usually caused by the epstein-barr virus)
- Oesophageal candidiasis (fungal infection of oesophagus)
- Toxicoderma (a disease of the skin caused by a toxic agent)
10-19:
- Chills (felling of cold)
- Disease recurrence
- Nephropathy toxic (damage to kidney due to toxins)
- Drug ineffective
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Drug resistance (reduction in effectiveness of a drug)
- Extradural abscess (pus may gather between a patient's skull and his dura)
- Hepatocellular injury (liver injury)
- Hepatomegaly (abnormal enlargement of the liver)
20-29:
- Hepatic function abnormal
- Pneumonia
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood alkaline phosphatase nos increased
- Blood bilirubin increased
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
- Multi-organ failure (multisystem organ failure)
- Renal impairment (severely reduced kidney function)
30-39:
- Drug ineffective
- Visual impairment
- Cryptococcosis (potentially fatal fungal disease)
- Drug resistance (reduction in effectiveness of a drug)
- Lung disorder (lung disease)
- Pyrexia (fever)
- Abortion missed (delayed or silent miscarriage)
- Abortion spontaneous (naturally occurring miscarriage)
- Acute respiratory distress syndrome
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
40-49:
- Multi-organ failure (multisystem organ failure)
- Blood creatinine increased
- Depressed level of consciousness
- Fatigue (feeling of tiredness)
- Ketoacidosis (high concentrations of ketone bodies in blood)
- Malaise (a feeling of general discomfort or uneasiness)
- Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
- Neutropenia (an abnormally low number of neutrophils)
- Rash pustular (redness with pustules)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
50-59:
- Myoglobinuria present (presence of myoglobin in the urine)
- Myopathy (a muscular disease in which the muscle fibres do not function)
- Nausea (feeling of having an urge to vomit)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Pain in limb
- Pneumonia
- Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
- Purulent discharge (discharge that contains pus)
- Pyrexia (fever)
- Red blood cell count decreased
60+:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Endocarditis bacterial (an inflammation of the inner layer of the heart by bacterial infection)
- General physical health deterioration (weak health status)
- Hepatic function abnormal
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Hypotension (abnormally low blood pressure)
- Orbital apex syndrome (a collection of cranial nerve deficits associated with a mass lesion near the apex of the orbit of the eye)
- Pain in jaw
What are the existing conditions these people have? *
- Chills (felling of cold): 8 people, 8.60%
- Histoplasmosis Disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum): 7 people, 7.53%
- Immunodeficiency Common Variable: 6 people, 6.45%
* Approximation only. Some reports may have incomplete information.
Do you take Amphotericin b and Sporanox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Amphotericin b (16,275 reports)
- Sporanox (6,137 reports)
Browse all drug interactions of Amphotericin b and Sporanox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Amphotericin b:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sporanox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amphotericin b and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sporanox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amphotericin b and itraconazole (the active ingredients of Amphotericin b and Sporanox, respectively), and Amphotericin b and Sporanox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Loraz cause Loss Of Libido? - 13 seconds ago
- Drug interactions of Venlafaxine Hydrochloride and Nexplanon - 25 seconds ago
- Drug interactions of Warfarin Sodium and Midazolam - 51 seconds ago
- Iron Overload and Neutrophil Count Increased - a minute ago
- Could Darifenacin cause Delirium? - a minute ago
- Drug interactions of Glipizide and Perjeta - a minute ago
- Losartan Potassium; Hydrochlorothiazide vs. Accupril, side effect and effectiveness comparison - 2 minutes ago
- Could Ritalin cause Homicidal Ideation? - 2 minutes ago
- Could Zerit cause Rickets? - 2 minutes ago
- Could Tenormin cause Ards (Acute Respiratory Distress Syndrome)? - 3 minutes ago