Amphotericin b and Zidovudine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amphotericin b (amphotericin b) and Zidovudine (zidovudine). Common drug interactions include encephalopathy among females and cryptococcosis among males.

The phase IV clinical study analyzes what interactions people have when they take Amphotericin b and Zidovudine. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Amphotericin b?

Amphotericin b has active ingredients of amphotericin b. It is often used in thrush. eHealthMe is studying from 16,275 Amphotericin b users. Check the latest studies of Amphotericin b.

What is Zidovudine?

Zidovudine has active ingredients of zidovudine. eHealthMe is studying from 10,517 Zidovudine users. Check the latest studies of Zidovudine.

On Aug, 05, 2026

79 people who take Amphotericin b and Zidovudine together, and have interactions are studied.

Amphotericin b and Zidovudine drug interactions.

What are the common drug interactions of Amphotericin B and Zidovudine, by gender? *:

female:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Gastric ulcer (stomach ulcer)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hepatotoxicity (chemical-driven liver damage)
Hypersensitivity
Oesophageal candidiasis (fungal infection of oesophagus)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Weight decreased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)

male:

Cryptococcosis (potentially fatal fungal disease)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Renal impairment (severely reduced kidney function)
Transaminases increased
Acute abdomen
Akinesia (loss of control of voluntary muscle movements)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Diarrhoea
Drug exposure during pregnancy
Hepatomegaly (abnormal enlargement of the liver)

What are the common drug interactions of Amphotericin B and Zidovudine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Chills (felling of cold)
Disease recurrence
Nephropathy toxic (damage to kidney due to toxins)
Drug ineffective

20-29:

Immune reconstitution syndrome (immune recovery syndrome)
Headache (pain in head)
Drug resistance (reduction in effectiveness of a drug)
Pneumonia
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Productive cough
Pyrexia (fever)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blindness
Blood creatinine increased

30-39:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Hepatic fibrosis (scarring process that represents the liver's response to injury)
Headache (pain in head)
Cryptococcosis (potentially fatal fungal disease)
Immune reconstitution syndrome (immune recovery syndrome)
Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Vomiting
Transaminases increased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

40-49:

Immune reconstitution syndrome (immune recovery syndrome)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophagia (reduced food intake)
Hypotension (abnormally low blood pressure)
Hypothalamo-pituitary disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Diarrhoea
Gastric ulcer (stomach ulcer)
Pancreatitis (inflammation of pancreas)
Renal failure acute (rapid kidney dysfunction)

50-59:

Blood creatinine increased
Crystalluria present
Dementia (madness)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Nephropathy (damage to or disease of a kidney)

60+:

Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Renal impairment (severely reduced kidney function)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)

What are the existing conditions these people have? *

Hiv Infection: 42 people, 53.16%
Oral Candidiasis (fungal infection of mouth): 7 people, 8.86%
Meningitis Cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 5 people, 6.33%
Chills (felling of cold): 5 people, 6.33%
Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 4 people, 5.06%
Immune Reconstitution Syndrome (immune recovery syndrome): 4 people, 5.06%
Histoplasmosis (infection caused by breathing in spores of a fungus): 4 people, 5.06%
Hepatitis C: 4 people, 5.06%
Drug Exposure During Pregnancy: 4 people, 5.06%
Cough: 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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