Amrix and Avonex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Amrix (cyclobenzaprine hydrochloride) and Avonex (interferon beta 1a). Common drug interactions include bronchitis among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Amrix and Avonex. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Amrix?
Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.
What is Avonex?
Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.
38 people who take Amrix and Avonex together, and have interactions are studied.

What are the common drug interactions of Amrix and Avonex, by gender? *:
female:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Infectious mononucleosis (infection usually caused by the epstein-barr virus)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pneumonia
- Diarrhoea
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Drug ineffective
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
male:
- Drug ineffective
- Fall
- Appetite disorder (abnormal eating habits)
- Fatigue (feeling of tiredness)
- Peripheral swelling
- Weight decreased
What are the common drug interactions of Amrix and Avonex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Diarrhoea
- Headache (pain in head)
- Epstein-barr virus infection
30-39:
n/a
40-49:
n/a
50-59:
- Pain
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gait disturbance
- Lung carcinoma cell type unspecified stage iv (the lung cancer has spread to other organs of the body, such as the other lung, brain, or liver)
- Neuropathy peripheral (surface nerve damage)
- Restless legs syndrome (a powerful urge to move your legs)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
60+:
- Alopecia (absence of hair from areas of the body)
- Diarrhoea
- Disability
- Heart rate decreased
- Hospitalisation
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Intervertebral disc protrusion (spinal disc protrusion)
- Lung cancer metastatic (lung cancer spreads to other parts)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Sinus disorder (disease of sinus)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 55.26%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 21 people, 55.26%
- Nausea (feeling of having an urge to vomit): 5 people, 13.16%
- Drowsiness: 3 people, 7.89%
- Vitamin D Decreased: 2 people, 5.26%
- Pain: 2 people, 5.26%
- Multiple Allergies (allergy to multiple agents): 2 people, 5.26%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.26%
- Headache (pain in head): 2 people, 5.26%
- Gait Disturbance: 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Amrix and Avonex?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Amrix and Avonex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Amrix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avonex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amrix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avonex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and interferon beta 1a (the active ingredients of Amrix and Avonex, respectively), and Amrix and Avonex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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