Anafranil and Amisulpride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anafranil (clomipramine hydrochloride) and Amisulpride (amisulpride). Common drug interactions include conjunctivitis among females and neuroleptic malignant syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Anafranil and Amisulpride. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Anafranil?

Anafranil has active ingredients of clomipramine hydrochloride. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 6,304 Anafranil users. Check the latest studies of Anafranil.

What is Amisulpride?

Amisulpride has active ingredients of amisulpride. eHealthMe is studying from 6,389 Amisulpride users. Check the latest studies of Amisulpride.

On Jul, 17, 2026

43 people who take Anafranil and Amisulpride together, and have interactions are studied.

Anafranil and Amisulpride drug interactions.

What are the common drug interactions of Anafranil and Amisulpride, by gender? *:

female:

Conjunctivitis (pink eye)
Constipation
Dry eye (lack of adequate tears)
Eye irritation
Intestinal obstruction
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Psoriasis (immune-mediated disease that affects the skin)
Vision blurred
Visual impairment
Adverse event

male:

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Cryptorchism
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Salivary hypersecretion (excess saliva secretion)
Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
Neonatal respiratory failure (a life-threatening condition in which respiratory function is inadequate to maintain the body's need for oxygen supply and carbon dioxide removal while at rest)
Persistent foetal circulation (baby's blood does not need to pass by the lungs)
Bradycardia (abnormally slow heart action)
Electrocardiogram qt prolonged
Collapse (sudden functional breakdown)

What are the common drug interactions of Anafranil and Amisulpride, by age (0-1 to 60+)? *:

0-1:

Cryptorchism
Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
Neonatal respiratory failure (a life-threatening condition in which respiratory function is inadequate to maintain the body's need for oxygen supply and carbon dioxide removal while at rest)
Persistent foetal circulation (baby's blood does not need to pass by the lungs)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

2-9:

n/a

10-19:

n/a

20-29:

Gestational diabetes (diabetes in pregnancy)
Maternal exposure during pregnancy (use of substance during pregnancy)
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)

30-39:

Collapse (sudden functional breakdown)
Dyspnoea (difficult or laboured respiration)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Salivary hypersecretion (excess saliva secretion)

40-49:

Conjunctivitis (pink eye)
Constipation
Dry eye (lack of adequate tears)
Eye irritation
Intestinal obstruction
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Psoriasis (immune-mediated disease that affects the skin)
Vision blurred
Visual impairment
Adverse event

50-59:

Bradycardia (abnormally slow heart action)
Electrocardiogram qt prolonged

60+:

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Cardiogenic shock (inadequate circulation of blood)
Lethargy (tiredness)
Tremor (trembling or shaking movements in one or more parts of your body)
Circulatory collapse
Hypoxia (low oxygen in tissues)
Livedo reticularis (a lace-like purplish discoloration of the skin)
Respiratory rate increased (excess breathing rate/min)
Cor pulmonale acute (rapid enlargement of the right ventricle of the heart)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Depression: 31 people, 72.09%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 9.30%
High Blood Pressure: 4 people, 9.30%
Bipolar Disorder (mood disorder): 4 people, 9.30%
Asthma: 4 people, 9.30%
Gestational Diabetes (diabetes in pregnancy): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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