Anafranil and Zavesca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anafranil (clomipramine hydrochloride) and Zavesca (miglustat). Common drug interactions include convulsion among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Anafranil and Zavesca. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Anafranil?

Anafranil has active ingredients of clomipramine hydrochloride. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 6,304 Anafranil users. Check the latest studies of Anafranil.

What is Zavesca?

Zavesca has active ingredients of miglustat. eHealthMe is studying from 1,208 Zavesca users. Check the latest studies of Zavesca.

On Jul, 16, 2026

17 people who take Anafranil and Zavesca together, and have interactions are studied.

Anafranil and Zavesca drug interactions.

What are the common drug interactions of Anafranil and Zavesca, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Eye movement disorder
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Neuropathy peripheral (surface nerve damage)
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Oedema peripheral (superficial swelling)
Rash
Red blood cell sedimentation rate increased
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Streptococcus test positive

male:

Diarrhoea
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Decreased appetite
Epistaxis (bleed from the nose)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Disease progression
Anal abscess
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abscess limb (limb infection)
Anaemia (lack of blood)

What are the common drug interactions of Anafranil and Zavesca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

General physical health deterioration (weak health status)
Weight decreased
Abdominal pain
Asthenia (weakness)
Decreased appetite
Epistaxis (bleed from the nose)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Disease progression
Anal abscess
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

10-19:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Diarrhoea
Gastroenteritis (inflammation of stomach and intestine)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Eye movement disorder
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Neuropathy peripheral (surface nerve damage)
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))

20-29:

n/a

30-39:

Coagulation factor decreased (less clotting substance in blood)
Ear haemorrhage (bleeding from ear)
Epistaxis (bleed from the nose)
Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
Platelet count decreased
Renal failure neonatal (kidney failure in baby less than a year)
Respiratory depression (respiration has a rate below 12 breaths)
Thrombocytopenia (decrease of platelets in blood)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 23.53%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 17.65%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 17.65%
Respiratory Tract Inflammation: 1 person, 5.88%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 1 person, 5.88%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 5.88%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.88%
Back Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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