Anaprox and Prozac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anaprox (naproxen sodium) and Prozac (fluoxetine hydrochloride). Common drug interactions include pyrexia among females and arrhythmia among males.

The phase IV clinical study analyzes what interactions people have when they take Anaprox and Prozac. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Anaprox?

Anaprox has active ingredients of naproxen sodium. eHealthMe is studying from 1,370 Anaprox users. Check the latest studies of Anaprox.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

On Jul, 27, 2026

62 people who take Anaprox and Prozac together, and have interactions are studied.

What are the common drug interactions of Anaprox and Prozac, by gender? *:

female:

Pyrexia (fever)
Rash
Renal failure (kidney dysfunction)
Sedation
Sleep disorder
Stomatitis (inflammation of mucous membrane of mouth)
Upper respiratory tract infection
Vertigo
Viral infection
Acanthoma (a skin cancer)

male:

Arrhythmia (irregular heartbeat)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Essential hypertension (primary hypertension)
Eye disorder
General physical health deterioration (weak health status)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Impaired work ability

What are the common drug interactions of Anaprox and Prozac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Dehydration (dryness resulting from the removal of water)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Migraine (headache)
Nervousness
Organ failure
Photosensitivity reaction
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

20-29:

Emotional distress
Pain
Gallbladder disorder
Blood triglycerides increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyperhomocysteinaemia (abnormally high level of homocysteine in the blood)
Neuropathy peripheral (surface nerve damage)
Type 2 diabetes mellitus

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Drug dependence
Exacerbation of anxiety (increase in the severity of anxiety)
Anger
Sedation
Acute myocardial infarction (acute heart attack)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Ataxia (loss of full control of bodily movements)
Chest pain
Cough

40-49:

Lacrimation increased
Lethargy (tiredness)
Limb injury
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Mitral valve prolapse (heart's mitral valve doesn't work well)
Myocarditis (inflammation of heart muscle myocardium)
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Photosensitivity reaction

50-59:

Arrhythmia (irregular heartbeat)
Breast cancer in situ
Nausea (feeling of having an urge to vomit)
Abdominal pain
Asthma
Breast cancer
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Cardiomegaly (increased size of heart than normal)
Chest pain

60+:

Diarrhoea
Drug hypersensitivity
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Delirium (wild excitement)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspepsia (indigestion)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Emotional distress
Eye disorder
General physical health deterioration (weak health status)

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 14.52%
Pain: 8 people, 12.90%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 7 people, 11.29%
Stress And Anxiety: 6 people, 9.68%
Postpartum Depression (depression suffered by a mother following childbirth): 6 people, 9.68%
Diabetes: 6 people, 9.68%
Menopausal Symptoms: 5 people, 8.06%
Birth Control: 5 people, 8.06%

* Approximation only. Some reports may have incomplete information.

Do you take Anaprox and Prozac?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously