Anastrozole and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anastrozole (anastrozole) and Actonel (risedronate sodium). Common drug interactions include bone pain among females.

The phase IV clinical study analyzes what interactions people have when they take Anastrozole and Actonel. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Anastrozole?

Anastrozole has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 21,892 Anastrozole users. Check the latest studies of Anastrozole.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.



On Jul, 11, 2026

48 people who take Anastrozole and Actonel together, and have interactions are studied.

Anastrozole and Actonel drug interactions.

What are the common drug interactions of Anastrozole and Actonel, by gender? *:

female:

  1. Bone pain
  2. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Bacterial test positive
  5. Bone disorder
  6. Bone formation increased
  7. Breast atrophy (overly enlarged breasts)
  8. Decreased appetite
  9. Decreased interest
  10. Dehydration (dryness resulting from the removal of water)

male:

n/a

What are the common drug interactions of Anastrozole and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Burning sensation
  2. Abdominal pain
  3. Abdominal pain lower
  4. Ageusia (loss of taste functions of the tongue)
  5. Alopecia (absence of hair from areas of the body)
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Anaemia (lack of blood)
  8. Anosmia (partial or complete loss of the sense of smell)
  9. Anxiety
  10. Arteriosclerosis (thickening and hardening of arteries)

30-39:

n/a

40-49:

  1. Migraine (headache)

50-59:

  1. Cardiac flutter (abnormal heart rhythm)
  2. Confusional state
  3. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  4. Dizziness
  5. Dysuria (painful or difficult urination)
  6. Gait disturbance
  7. Haematochezia (passage of stools containing blood)
  8. Headache (pain in head)
  9. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  10. Mucous stools (mucous with stool)

60+:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Myalgia (muscle pain)
  3. Fall
  4. Hip fracture
  5. Abdominal discomfort
  6. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  7. Aortic valve stenosis (narrowing of the aortic valve)
  8. Aphthous stomatitis (mouth ulcer)
  9. Aphthous ulcer (mouth ulcer)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

  1. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 8 people, 16.67%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 16.67%
  3. Abdominal Pain Upper: 8 people, 16.67%
  4. Depression: 7 people, 14.58%
  5. Metastases To Bone (cancer spreads to bone): 6 people, 12.50%
  6. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 6 people, 12.50%
  7. Cystitis Interstitial (unknown cause characterized by bladder pain): 6 people, 12.50%
  8. Breast Cancer Metastatic: 6 people, 12.50%
  9. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Anastrozole and Actonel?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Anastrozole and Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Anastrozole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anastrozole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actonel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on anastrozole and risedronate sodium (the active ingredients of Anastrozole and Actonel, respectively), and Anastrozole and Actonel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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