Anastrozole and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anastrozole (anastrozole) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include nausea among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Anastrozole and Bactrim ds. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Anastrozole?

Anastrozole has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 21,892 Anastrozole users. Check the latest studies of Anastrozole.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.



On Jul, 05, 2026

63 people who take Anastrozole and Bactrim ds together, and have interactions are studied.

Anastrozole and Bactrim ds drug interactions.

What are the common drug interactions of Anastrozole and Bactrim Ds, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Muscle spasms (muscle contraction)
  3. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  4. Fatigue (feeling of tiredness)
  5. Abdominal pain
  6. Depression
  7. Emotional distress
  8. General physical health deterioration (weak health status)
  9. Osteomyelitis (infection of bone)
  10. Osteonecrosis of jaw (death of bone of jaw)

male:

  1. Cough
  2. Fatigue (feeling of tiredness)
  3. Insomnia (sleeplessness)
  4. Local swelling (swelling at the site of some application of substance or injury)
  5. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)

What are the common drug interactions of Anastrozole and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Alopecia (absence of hair from areas of the body)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Bone pain
  5. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  6. Drug hypersensitivity
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hot flush (sudden feelings of heat)
  9. Lymphoedema (localized fluid retention and tissue swelling)
  10. Nausea (feeling of having an urge to vomit)

40-49:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Depression
  4. Emotional distress
  5. General physical health deterioration (weak health status)
  6. Osteomyelitis (infection of bone)
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Pain
  9. Pain in jaw
  10. Anxiety

50-59:

  1. Impaired healing
  2. Insomnia (sleeplessness)
  3. Neuropathy peripheral (surface nerve damage)
  4. Peripheral swelling
  5. Pneumonia
  6. Rash pruritic (redness with itching)
  7. Rash pustular (redness with pustules)
  8. Skin mass
  9. Urinary hesitation (difficulty in beginning the flow of urine)
  10. Urinary retention (the inability to completely or partially empty the bladder)

60+:

  1. Fatigue (feeling of tiredness)
  2. Arthralgia (joint pain)
  3. Vomiting
  4. White blood cell count decreased
  5. Abdominal pain
  6. Anaemia (lack of blood)
  7. Anastomotic leak
  8. Anxiety
  9. Atelectasis (partial or complete collapse of the lung)
  10. Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 19.05%
  2. Breast Cancer Female: 12 people, 19.05%
  3. Stress And Anxiety: 7 people, 11.11%
  4. Nausea And Vomiting: 7 people, 11.11%
  5. Nausea (feeling of having an urge to vomit): 7 people, 11.11%
  6. Metastases To Bone (cancer spreads to bone): 7 people, 11.11%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 9.52%
  8. Breast Cancer Metastatic: 6 people, 9.52%
  9. Gait Disturbance: 5 people, 7.94%
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Anastrozole and Bactrim ds:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Anastrozole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bactrim ds:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anastrozole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bactrim ds and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on anastrozole and sulfamethoxazole; trimethoprim (the active ingredients of Anastrozole and Bactrim ds, respectively), and Anastrozole and Bactrim ds (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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