Ancef and Vivelle drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ancef (cefazolin sodium) and Vivelle (estradiol). Common drug interactions include lymphopenia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Ancef and Vivelle. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Ancef?

Ancef has active ingredients of cefazolin sodium. eHealthMe is studying from 3,292 Ancef users. Check the latest studies of Ancef.

What is Vivelle?

Vivelle has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,624 Vivelle users. Check the latest studies of Vivelle.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

14 people who take Ancef and Vivelle together, and have interactions are studied.

What are the common drug interactions of Ancef and Vivelle, by gender? *:

female:

Lymphopenia (an abnormally low level of lymphocytes in the blood)
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)
Vomiting
Ileus (a painful obstruction of the ileum or other part of the intestine)
Urinary retention (the inability to completely or partially empty the bladder)
Dysuria (painful or difficult urination)

male:

Arthralgia (joint pain)
Back pain
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Deformity (disfigurement)
Dental caries
Disability
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness

What are the common drug interactions of Ancef and Vivelle, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dysuria (painful or difficult urination)
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)
Vomiting
Ileus (a painful obstruction of the ileum or other part of the intestine)
Urinary retention (the inability to completely or partially empty the bladder)

40-49:

n/a

50-59:

Lymphopenia (an abnormally low level of lymphocytes in the blood)

60+:

Abdominal pain
Affective disorder (mental disorder)
Aortic valve sclerosis (narrowing of the aortic valve)
Apathy
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Balance disorder

What are the existing conditions these people have? *

Metastases To Prostate (cancer spreads to prostate): 7 people, 50.00%
Metastases To Bone (cancer spreads to bone): 7 people, 50.00%
Procedural Pain: 6 people, 42.86%
Pain: 3 people, 21.43%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 7.14%
Stress And Anxiety: 1 person, 7.14%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.14%
Panic Disorder: 1 person, 7.14%
Osteoporotic Fracture (fracture due to weak bone): 1 person, 7.14%
Osteoporosis (bones weak and more likely to break): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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