Antabuse and Risperdal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Antabuse (disulfiram) and Risperdal (risperidone). Common drug interactions include dissociation among females and mydriasis among males.
The phase IV clinical study analyzes what interactions people have when they take Antabuse and Risperdal. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Antabuse?
Antabuse has active ingredients of disulfiram. It is often used in alcoholism. eHealthMe is studying from 1,182 Antabuse users. Check the latest studies of Antabuse.
What is Risperdal?
Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.
32 people who take Antabuse and Risperdal together, and have interactions are studied.

What are the common drug interactions of Antabuse and Risperdal, by gender? *:
female:
- Dissociation
- Mania (a state of abnormally elevated or irritable mood)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Anaemia (lack of blood)
- Bacterial infection
- Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
- Blood cholesterol increased
- Depressed level of consciousness
- Depressed mood
- Difficulty in walking
male:
- Mydriasis (a dilation of the pupil)
- Self injurious behaviour
- Overdose
- Abdominal pain upper
- Affective disorder (mental disorder)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Asthenia (weakness)
- Blindness
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Confusional state
What are the common drug interactions of Antabuse and Risperdal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Mydriasis (a dilation of the pupil)
- Self injurious behaviour
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Multiple drug overdose intentional
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Abdominal pain upper
- Affective disorder (mental disorder)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Asthenia (weakness)
- Blindness
30-39:
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Obesity (having too much body fat)
- Overdose
- Pancreatitis (inflammation of pancreas)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Suicide attempt
- Tardive dyskinesia (a disorder that involves involuntary movements)
- Type 2 diabetes mellitus
- Vomiting
40-49:
- Hypotension (abnormally low blood pressure)
- Anger
- Anxiety
- Contusion (a type of hematoma of tissue in which capillaries)
- Depression
- Diabetes mellitus non-insulin-dependent
- Disturbance in attention
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Dizziness
- Fatigue (feeling of tiredness)
50-59:
- Diabetes mellitus inadequate control
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Dyskinesia (abnormality or impairment of voluntary movement)
- General physical health deterioration (weak health status)
- Hypokalaemia (low potassium)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Neuropathy peripheral (surface nerve damage)
- Neutropenia (an abnormally low number of neutrophils)
- Poisoning
- Tardive dyskinesia (a disorder that involves involuntary movements)
60+:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hypotension (abnormally low blood pressure)
What are the existing conditions these people have? *
- Sleep Disorder: 3 people, 9.38%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 9.38%
- Pain: 3 people, 9.38%
- Stress And Anxiety: 2 people, 6.25%
- Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 6.25%
- Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Antabuse and Risperdal?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Antabuse and Risperdal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Antabuse:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Risperdal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Antabuse and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Risperdal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on disulfiram and risperidone (the active ingredients of Antabuse and Risperdal, respectively), and Antabuse and Risperdal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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