Anusol hc and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anusol hc (hydrocortisone) and Oxycodone (oxycodone hydrochloride). Common drug interactions include nail bed tenderness among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Anusol hc and Oxycodone. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Anusol hc?

Anusol hc has active ingredients of hydrocortisone. It is often used in hemorrhoids. eHealthMe is studying from 679 Anusol hc users. Check the latest studies of Anusol hc.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

On Jul, 28, 2026

42 people who take Anusol hc and Oxycodone together, and have interactions are studied.

Anusol hc and Oxycodone drug interactions.

What are the common drug interactions of Anusol Hc and Oxycodone, by gender? *:

female:

Nail bed tenderness
Neuropathy peripheral (surface nerve damage)
Skin discolouration (change of skin colour)
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Vaginal haemorrhage (vaginal bleeding)
Arthralgia (joint pain)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Abdominal pain
Dizziness
Headache (pain in head)

male:

Vomiting
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Anusol Hc and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Intestinal obstruction
Urinary tract infection

20-29:

Abdominal pain

30-39:

n/a

40-49:

Anaemia (lack of blood)
Diarrhoea
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Localised infection (infection at the single location)
Nail bed tenderness
Neuropathy peripheral (surface nerve damage)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Skin discolouration (change of skin colour)

50-59:

Neutropenia (an abnormally low number of neutrophils)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Vomiting
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Haemolytic anaemia (anaemia due to haemolysis)
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)

60+:

Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Disturbance in attention
Drug dependence
Dysphemia (stammering or stuttering)
Dyspnoea (difficult or laboured respiration)
Feeling jittery
Hypertension (high blood pressure)
Infertility female

What are the existing conditions these people have? *

Bone Disorder: 14 people, 33.33%
Acetabulum Fracture (socket of the hip joint- fracture): 14 people, 33.33%
Breast Cancer Metastatic: 11 people, 26.19%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 4 people, 9.52%
Insomnia (sleeplessness): 4 people, 9.52%
High Blood Pressure: 4 people, 9.52%
Stress And Anxiety: 3 people, 7.14%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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