Anusol hc and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anusol hc (hydrocortisone) and Prilosec (omeprazole). Common drug interactions include back pain among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Anusol hc and Prilosec. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Anusol hc?

Anusol hc has active ingredients of hydrocortisone. It is often used in hemorrhoids. eHealthMe is studying from 679 Anusol hc users. Check the latest studies of Anusol hc.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.



On Jul, 16, 2026

52 people who take Anusol hc and Prilosec together, and have interactions are studied.

Anusol hc and Prilosec drug interactions.

What are the common drug interactions of Anusol Hc and Prilosec, by gender? *:

female:

  1. Back pain
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Constipation
  4. Dizziness
  5. Fatigue (feeling of tiredness)
  6. Haematocrit decreased
  7. Haemoglobin decreased
  8. Hypertension (high blood pressure)
  9. Injury
  10. Pain

male:

  1. Back pain
  2. Fatigue (feeling of tiredness)
  3. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  4. Pneumonia
  5. Post procedural infection
  6. Psoriasis (immune-mediated disease that affects the skin)
  7. Arthralgia (joint pain)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Pain in extremity
  10. Abdominal distension

What are the common drug interactions of Anusol Hc and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal distension
  2. Abdominal pain upper
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Cholecystitis chronic (long lasting infection of gallbladder)
  6. Diarrhoea
  7. Emotional distress
  8. Gallbladder disorder
  9. Gastroenteritis eosinophilic (white blood cell deposits in tissue of stomach or intestine with infection)
  10. General physical health deterioration (weak health status)

20-29:

n/a

30-39:

n/a

40-49:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Drug ineffective
  3. Fibromyalgia (a long-term condition which causes pain all over the body)
  4. Hypertension (high blood pressure)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Iron deficiency anaemia
  7. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  8. Muscle spasms (muscle contraction)
  9. Muscle tightness
  10. Photosensitivity reaction

50-59:

  1. Abdominal distension
  2. Abdominal pain upper
  3. Asthenia (weakness)
  4. Back pain
  5. Dry skin
  6. Dyspepsia (indigestion)
  7. Pancreatitis (inflammation of pancreas)
  8. Rash generalised (rash on most of body parts)
  9. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  10. Alopecia (absence of hair from areas of the body)

60+:

  1. Back pain
  2. Fatigue (feeling of tiredness)
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Constipation
  6. Cough
  7. Dizziness
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

What are the existing conditions these people have? *

  1. Pain: 7 people, 13.46%
  2. Nausea (feeling of having an urge to vomit): 6 people, 11.54%
  3. Osteoporosis (bones weak and more likely to break): 5 people, 9.62%
  4. Stress And Anxiety: 4 people, 7.69%
  5. Multiple Myeloma (cancer of the plasma cells): 4 people, 7.69%
  6. Chest Pain: 4 people, 7.69%
  7. Sleep Disorder: 3 people, 5.77%
  8. Neuropathy Peripheral (surface nerve damage): 3 people, 5.77%
  9. Neuralgia (pain in one or more nerves): 3 people, 5.77%
  10. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Anusol hc and Prilosec?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Anusol hc and Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Anusol hc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anusol hc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone and omeprazole (the active ingredients of Anusol hc and Prilosec, respectively), and Anusol hc and Prilosec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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