Apidra and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apidra (insulin glulisine recombinant) and Prilosec (omeprazole). Common drug interactions include arterial occlusive disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Apidra and Prilosec. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Apidra?

Apidra has active ingredients of insulin glulisine recombinant. It is often used in diabetes. eHealthMe is studying from 10,548 Apidra users. Check the latest studies of Apidra.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

On Jul, 11, 2026

93 people who take Apidra and Prilosec together, and have interactions are studied.

What are the common drug interactions of Apidra and Prilosec, by gender? *:

female:

Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Asthma
Balance disorder
Bladder disorder
Blood calcium decreased
Blood creatinine increased
Blood potassium decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus inadequate control

male:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Gout (uric acid crystals building up in the body)
Hypersensitivity
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Impaired healing
Malaise (a feeling of general discomfort or uneasiness)
Post procedural drainage
Renal injury (kidney injury)

What are the common drug interactions of Apidra and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Chronic kidney disease

10-19:

n/a

20-29:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
Pulmonary embolism (blockage of the main artery of the lung)
Renal vein thrombosis (blood clot in renal vein)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

30-39:

Injection site inflammation
Injection site necrosis (death of body tissue at injection site)
Injection site pain

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Pulmonary embolism (blockage of the main artery of the lung)
Cough

50-59:

Nausea (feeling of having an urge to vomit)
Pain in extremity
Post procedural drainage
Renal injury (kidney injury)
Sinusitis (inflammation of sinus)
Body temperature increased
Gait disturbance
Impaired work ability
Pain
Abdominal discomfort

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Urinary tract infection
Hyperhidrosis (abnormally increased sweating)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Renal injury (kidney injury)

What are the existing conditions these people have? *

High Blood Pressure: 32 people, 34.41%
High Blood Cholesterol: 22 people, 23.66%
Pain: 21 people, 22.58%
Stress And Anxiety: 15 people, 16.13%
Depression: 12 people, 12.90%
Indigestion: 9 people, 9.68%
Type 2 Diabetes: 8 people, 8.60%
Oedema (fluid collection in tissue): 8 people, 8.60%
Cardiac Disorder: 8 people, 8.60%
Fluid Retention (an abnormal accumulation of fluid in the blood): 7 people, 7.53%

* Approximation only. Some reports may have incomplete information.

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