Apidra and Zolpidem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apidra (insulin glulisine recombinant) and Zolpidem (zolpidem tartrate). Common drug interactions include hyperglycaemia among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Apidra and Zolpidem. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Apidra?

Apidra has active ingredients of insulin glulisine recombinant. It is often used in diabetes. eHealthMe is studying from 10,548 Apidra users. Check the latest studies of Apidra.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

On Aug, 12, 2026

77 people who take Apidra and Zolpidem together, and have interactions are studied.

What are the common drug interactions of Apidra and Zolpidem, by gender? *:

female:

Hyperglycaemia (high blood sugar)
Hypertension (high blood pressure)
Oedema (fluid collection in tissue)
Pneumonia
Renal failure acute (rapid kidney dysfunction)
Rhinorrhoea (watery mucus discharge from the nose)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood glucose increased
Breast cancer
Delirium (wild excitement)

male:

Thrombocytopenia (decrease of platelets in blood)
White blood cell count increased
General physical health deterioration (weak health status)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Sedation
Blood glucose increased
Chronic kidney disease
Gout (uric acid crystals building up in the body)
Renal failure (kidney dysfunction)
Abdominal distension

What are the common drug interactions of Apidra and Zolpidem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abnormal dreams
Sleep terror (felling of terror in sleep)

30-39:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

40-49:

Back pain
Blood creatinine increased
Blood urea increased
Burning sensation
Cervicobrachial syndrome (pain in neck and arm with changing location)
Confusional state
Cough
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Dizziness
Drug withdrawal convulsions

50-59:

Haematochezia (passage of stools containing blood)
Angina bullosa haemorrhagica (a condition of the mucous membranes characterized by the sudden appearance of one or more blood blisters within the oral cavity)
Gingival bleeding (bleeding gums)
Platelet count decreased
Thrombocytopenia (decrease of platelets in blood)
White blood cell count increased
Glycosylated haemoglobin increased
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal failure (kidney dysfunction)

60+:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Chest pain
Chronic kidney disease
Diabetic coma
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

High Blood Pressure: 19 people, 24.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 19.48%
Stress And Anxiety: 10 people, 12.99%
Fluid Retention (an abnormal accumulation of fluid in the blood): 10 people, 12.99%
Depression: 9 people, 11.69%
Pain: 8 people, 10.39%
Asthma: 8 people, 10.39%
Blood Pressure Abnormal: 8 people, 10.39%
Abdominal Pain Upper: 8 people, 10.39%
Type 2 Diabetes: 7 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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