Apixaban and Acetazolamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apixaban (apixaban) and Acetazolamide (acetazolamide). Common drug interactions include dyspnoea among females and disease progression among males.

The phase IV clinical study analyzes what interactions people have when they take Apixaban and Acetazolamide. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

What is Acetazolamide?

Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

26 people who take Apixaban and Acetazolamide together, and have interactions are studied.

Apixaban and Acetazolamide drug interactions.

What are the common drug interactions of Apixaban and Acetazolamide, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Constipation
Atelectasis (partial or complete collapse of the lung)
Chest pain
Decreased appetite
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Heart rate irregular
Hypoxia (low oxygen in tissues)
Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium)
Osteonecrosis of jaw (death of bone of jaw)

male:

Disease progression
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Bacteraemia (presence of bacteria in the blood)
Choroid melanoma (cancer tumour arise from the blood-vessel layer ""choroid"" beneath the retina)
Choroidal detachment (separation of vascular layer of the eye)
Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)
Device related infection
Dyspnoea (difficult or laboured respiration)
Forced expiratory volume decreased (decreased lung expired air volume)
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Apixaban and Acetazolamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cerebral venous thrombosis (clot in brains venous blood system)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)

20-29:

Abdominal pain upper
Body temperature increased
Cerebral haemorrhage (bleeding within the brain)
Cough
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Headache (pain in head)
Heart rate increased
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

Osteonecrosis of jaw (death of bone of jaw)
Cancer pain
Cataract (clouding of the lens inside the eye)
Depression
Fall
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)

50-59:

Hypokinesia (decreased bodily movement)
Ill-defined disorder
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Lymphoedema (localized fluid retention and tissue swelling)
Cough
Dyspnoea (difficult or laboured respiration)
Dyspnoea at rest (difficult or laboured breathing during rest)
Localised oedema (fluid retention in a particular part of the body)
Mitral valve incompetence (inefficient heart valve)
Oedema (fluid collection in tissue)

60+:

Constipation
Dyspnoea (difficult or laboured respiration)
Pleural effusion (water on the lungs)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Seborrhoeic keratosis (noncancerous (benign) skin growths that some people develop as they age. they often appear on the back or chest)
Visual impairment
Anxiety
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

Pain: 5 people, 19.23%
Hypercoagulation (increased tendency for clotting of the blood): 4 people, 15.38%
Metastases To Bone (cancer spreads to bone): 4 people, 15.38%
Breast Cancer: 4 people, 15.38%
High Blood Pressure: 4 people, 15.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 15.38%
Joint Pain: 4 people, 15.38%
Agitation (state of anxiety or nervous excitement): 4 people, 15.38%
Nausea (feeling of having an urge to vomit): 4 people, 15.38%
Nail Bed Inflammation (infection of nail bed): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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