Apixaban and Epipen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apixaban (apixaban) and Epipen (epinephrine). Common drug interactions include asthma among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Apixaban and Epipen. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

27 people who take Apixaban and Epipen together, and have interactions are studied.

What are the common drug interactions of Apixaban and Epipen, by gender? *:

female:

Asthma
Pain in extremity
Fatigue (feeling of tiredness)
Heart rate increased
Blood pressure decreased
Blood pressure increased
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)

male:

Cardiac arrest
Device failure
Cardiac failure
Lung transplant
Pulmonary hypertension (increase in blood pressure in the lung artery)
Right ventricular failure (right half of the heart fails to work)
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Swelling face
Decreased appetite

What are the common drug interactions of Apixaban and Epipen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthma
Blood pressure decreased
Blood pressure increased
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Forced expiratory volume decreased (decreased lung expired air volume)
Headache (pain in head)

40-49:

Cardiac failure
Lung transplant
Pulmonary hypertension (increase in blood pressure in the lung artery)
Right ventricular failure (right half of the heart fails to work)

50-59:

Asthma
Pain in extremity
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)
Back pain
Bone pain
Carpal tunnel decompression
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Fatigue (feeling of tiredness)

60+:

Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Swelling face
Decreased appetite
Fall
Head injury
Muscular weakness (muscle weakness)
Weight decreased
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 29.63%
Lower Respiratory Tract Infection: 8 people, 29.63%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 29.63%
Allergic Rhinitis: 8 people, 29.63%
Bleeding Disorders: 6 people, 22.22%
Pain: 4 people, 14.81%
Asthma: 3 people, 11.11%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 7.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.41%
Hypersensitivity: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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