Apixaban and Nitrolingual drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apixaban (apixaban) and Nitrolingual (nitroglycerin). Common drug interactions include palpitations among females and general physical health deterioration among males.

The phase IV clinical study analyzes what interactions people have when they take Apixaban and Nitrolingual. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

What is Nitrolingual?

Nitrolingual has active ingredients of nitroglycerin. eHealthMe is studying from 2,777 Nitrolingual users. Check the latest studies of Nitrolingual.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

50 people who take Apixaban and Nitrolingual together, and have interactions are studied.

Apixaban and Nitrolingual drug interactions.

What are the common drug interactions of Apixaban and Nitrolingual, by gender? *:

female:

  1. Palpitations (feelings or sensations that your heart is pounding or racing)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Thalamus haemorrhage (bleeding in thalamus)
  4. Anxiety
  5. Bladder transitional cell carcinoma recurrent (types of bladder cancer-recurrent)
  6. Bladder transitional cell carcinoma stage ii (types of bladder cancer stage ii)
  7. Decreased activity
  8. Emotional distress
  9. Exercise tolerance decreased
  10. Fear of disease

male:

  1. General physical health deterioration (weak health status)
  2. Electrocardiogram qt prolonged
  3. Staphylococcal infection (an infection with staphylococcus bacteria)
  4. Bowen's disease (early stage of skin cancer)
  5. Dizziness
  6. Ear neoplasm malignant (ear cancerous tumour)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Influenza
  9. Injection site swelling
  10. Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Apixaban and Nitrolingual, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. General physical health deterioration (weak health status)
  2. Electrocardiogram qt prolonged
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Faeces discoloured
  5. Fall
  6. Hypertensive crisis
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  9. Anaemia (lack of blood)
  10. Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the existing conditions these people have? *

  1. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 18.00%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 16.00%
  3. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 8.00%
  4. Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 3 people, 6.00%
  5. Splenomegaly (enlargement of spleen): 3 people, 6.00%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.00%
  7. Pain: 3 people, 6.00%
  8. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 3 people, 6.00%
  9. High Blood Pressure: 3 people, 6.00%
  10. Chest Pain: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Apixaban and Nitrolingual?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Apixaban and Nitrolingual:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nitrolingual:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Apixaban and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrolingual and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on apixaban and nitroglycerin (the active ingredients of Apixaban and Nitrolingual, respectively), and Apixaban and Nitrolingual (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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