Apixaban and Tagrisso drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Apixaban (apixaban) and Tagrisso (osimertinib mesylate). Common drug interactions include cerebrovascular accident among females and metastases to central nervous system among males.
The phase IV clinical study analyzes what interactions people have when they take Apixaban and Tagrisso. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Apixaban?
Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.
What is Tagrisso?
Tagrisso has active ingredients of osimertinib mesylate. eHealthMe is studying from 19,890 Tagrisso users. Check the latest studies of Tagrisso.
19 people who take Apixaban and Tagrisso together, and have interactions are studied.

What are the common drug interactions of Apixaban and Tagrisso, by gender? *:
female:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Cardiac failure
- Pneumonia
- Pulmonary alveolar haemorrhage (acute bleeding)
- Arterial haemorrhage
- Asthenia (weakness)
- Cerebral artery thrombosis (clot formation in brain blood vessels)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Platelet count decreased
- Respiratory failure (inadequate gas exchange by the respiratory system)
male:
- Metastases to central nervous system (cancer spreads to central nervous system)
- Agitation (state of anxiety or nervous excitement)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Delirium (wild excitement)
- Fatigue (feeling of tiredness)
- Thought blocking (a sudden inability to finish a thought)
- Malignant neoplasm progression (cancer tumour came back)
- Cerebral disorder (brain disease)
- Pulmonary thrombosis (scarring in the lungs)
- Thrombosis (formation of a blood clot inside a blood vessel)
What are the common drug interactions of Apixaban and Tagrisso, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Back pain
40-49:
- Lung adenocarcinoma metastatic (a form of non-small cell lung cancer spreads to other part)
50-59:
- Embolic stroke (stroke due to obstruction due to an embolus)
60+:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Cardiac failure
- Thrombocytopenia (decrease of platelets in blood)
- White blood cell count increased
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Decreased interest
- Fatigue (feeling of tiredness)
- Malignant neoplasm progression (cancer tumour came back)
- Otitis media (inflammation of the middle ear)
- Pneumonia
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 8 people, 42.11%
- Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 10.53%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 2 people, 10.53%
- Embolism Venous (embolus may pass into the arterial system): 2 people, 10.53%
- Skin Cancer: 1 person, 5.26%
- Non-Small Cell Lung Cancer Stage Iv: 1 person, 5.26%
- Neoplasm Malignant (cancer tumour): 1 person, 5.26%
- Metastases To Bone (cancer spreads to bone): 1 person, 5.26%
- Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Apixaban and Tagrisso?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Apixaban and Tagrisso:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Apixaban:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tagrisso:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Apixaban and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tagrisso and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on apixaban and osimertinib mesylate (the active ingredients of Apixaban and Tagrisso, respectively), and Apixaban and Tagrisso (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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