Apokyn and Miralax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apokyn (apomorphine hydrochloride) and Miralax (polyethylene glycol 3350). Common drug interactions include nonspecific reaction among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Apokyn and Miralax. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Apokyn?

Apokyn has active ingredients of apomorphine hydrochloride. eHealthMe is studying from 5,284 Apokyn users. Check the latest studies of Apokyn.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.



On Aug, 02, 2026

91 people who take Apokyn and Miralax together, and have interactions are studied.

Apokyn and Miralax drug interactions.

What are the common drug interactions of Apokyn and Miralax, by gender? *:

female:

  1. Nonspecific reaction (unspecified reaction)
  2. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  3. Sneezing
  4. Gait disturbance
  5. Rhinorrhoea (watery mucus discharge from the nose)
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Cough
  8. Dementia (madness)
  9. Dystonia (abnormal muscle tone)
  10. Fatigue (feeling of tiredness)

male:

  1. Fall
  2. Nausea (feeling of having an urge to vomit)
  3. Sinus disorder (disease of sinus)
  4. Asthenia (weakness)
  5. Confusional state
  6. Heart rate increased
  7. Hyperhidrosis (abnormally increased sweating)
  8. Cough
  9. Gait disturbance
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Apokyn and Miralax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Injection site pruritus (severe itching at injection site)
  2. Insomnia (sleeplessness)
  3. Diarrhoea

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Dizziness
  3. Fall
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Anxiety
  6. Euphoric mood (excessively happy but may become angry or irritable)
  7. Heart rate increased
  8. Compulsive shopping
  9. Hyperhidrosis (abnormally increased sweating)
  10. Impulse-control disorder

60+:

  1. Fall
  2. Dizziness
  3. Confusional state
  4. Fatigue (feeling of tiredness)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Blood pressure increased
  7. Drug ineffective
  8. Hyperhidrosis (abnormally increased sweating)
  9. Agitation (state of anxiety or nervous excitement)
  10. Cough

What are the existing conditions these people have? *

  1. Parkinson's Disease: 81 people, 89.01%
  2. Hallucinations (sensations that appear real but are created by your mind): 9 people, 9.89%
  3. Stress And Anxiety: 8 people, 8.79%
  4. Nausea (feeling of having an urge to vomit): 7 people, 7.69%
  5. Pain: 6 people, 6.59%
  6. On And Off Phenomenon: 6 people, 6.59%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.59%
  8. Delusion (a false belief or opinion): 6 people, 6.59%

* Approximation only. Some reports may have incomplete information.

Do you take Apokyn and Miralax?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Apokyn and Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Apokyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Apokyn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Miralax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on apomorphine hydrochloride and polyethylene glycol 3350 (the active ingredients of Apokyn and Miralax, respectively), and Apokyn and Miralax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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