Apremilast and Percocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apremilast (apremilast) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include malaise among females.

The phase IV clinical study analyzes what interactions people have when they take Apremilast and Percocet. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Apremilast?

Apremilast has active ingredients of apremilast. eHealthMe is studying from 4,162 Apremilast users. Check the latest studies of Apremilast.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

On Jul, 21, 2026

32 people who take Apremilast and Percocet together, and have interactions are studied.

Apremilast and Percocet drug interactions.

What are the common drug interactions of Apremilast and Percocet, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Pruritus (severe itching of the skin)
Hand deformity
Hypoaesthesia (reduced sense of touch or sensation)
Vomiting
Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Pyrexia (fever)
Rash

male:

n/a

What are the common drug interactions of Apremilast and Percocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Malaise (a feeling of general discomfort or uneasiness)
Pruritus (severe itching of the skin)
Hand deformity
Hypoaesthesia (reduced sense of touch or sensation)
Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Pyrexia (fever)
Rash
Rheumatoid factor positive

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 29 people, 90.62%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 29 people, 90.62%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 24 people, 75.00%
Stress And Anxiety: 17 people, 53.12%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 12.50%
Inflammation: 4 people, 12.50%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 4 people, 12.50%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 9.38%
Back Pain: 3 people, 9.38%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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