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Aprepitant and Cosopt drug interactions - a phase IV clinical study of FDA data

Summary:

The phase IV clinical study analyzes what interactions people have when they take Aprepitant and Cosopt. It is created by eHealthMe based on reports of 4 people who take the same drugs from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

On Jun, 15, 2026

4 people who take Aprepitant and Cosopt together, and have interactions are studied.

Aprepitant and Cosopt drug interactions.

What are the common drug interactions of Aprepitant and Cosopt, by gender? *:

female:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Pyrexia (fever)
  4. Rash
  5. Rash erythematous (redness of the skin)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Vomiting

male:

  1. Asthenia (weakness)
  2. Decreased appetite
  3. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
  4. Dysgeusia (disorder of the sense of taste)
  5. Fatigue (feeling of tiredness)
  6. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  7. Hypercapnia (too much smoke)
  8. Memory impairment
  9. Muscular weakness (muscle weakness)
  10. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the common drug interactions of Aprepitant and Cosopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Asthenia (weakness)
  2. Decreased appetite
  3. Nausea (feeling of having an urge to vomit)
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Pyrexia (fever)
  6. Rash
  7. Rash erythematous (redness of the skin)
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Vomiting
  10. Diarrhoea

* Approximation only. Some reports may have incomplete information.

Do you take Aprepitant and Cosopt?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aprepitant and Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aprepitant and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cosopt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant and dorzolamide hydrochloride; timolol maleate (the active ingredients of Aprepitant and Cosopt, respectively), and Aprepitant and Cosopt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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