Aprepitant and Flurbiprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aprepitant (aprepitant) and Flurbiprofen (flurbiprofen). Common drug interactions include alanine aminotransferase increased among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Aprepitant and Flurbiprofen. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Flurbiprofen?

Flurbiprofen has active ingredients of flurbiprofen. It is often used in rheumatoid arthritis. eHealthMe is studying from 2,677 Flurbiprofen users. Check the latest studies of Flurbiprofen.

On Jul, 19, 2026

15 people who take Aprepitant and Flurbiprofen together, and have interactions are studied.

Aprepitant and Flurbiprofen drug interactions.

What are the common drug interactions of Aprepitant and Flurbiprofen, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Diarrhoea
Drug eruption (adverse drug reaction of the skin)
Nausea (feeling of having an urge to vomit)
Pneumonia
Rash
Vomiting
Myelosuppression (a decrease in the production of blood cells)
Ascites (accumulation of fluid in the abdominal cavity)

male:

Diarrhoea
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Electrocardiogram t wave inversion
Febrile neutropenia (fever with reduced white blood cells)
Intestinal perforation (complete penetration of the wall of the intestine)
Jejunal perforation (a hole in jejunum)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Aprepitant and Flurbiprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Haemorrhoids (a swollen vein or group of veins in the region of the anus)

50-59:

Diarrhoea
Myelosuppression (a decrease in the production of blood cells)
Duodenal perforation (complication of duodenal ulcer)
Duodenal ulcer

60+:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal impairment (severely reduced kidney function)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Ascites (accumulation of fluid in the abdominal cavity)
Decreased appetite
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Electrocardiogram t wave inversion

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 5 people, 33.33%
Nausea And Vomiting: 5 people, 33.33%
High Blood Pressure: 4 people, 26.67%
Constipation: 4 people, 26.67%
Rashes (redness): 3 people, 20.00%
Insomnia (sleeplessness): 3 people, 20.00%
Tumor Pain: 3 people, 20.00%
Allergies: 3 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
Diabetes: 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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