Apresoline and Atacand drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apresoline (hydralazine hydrochloride) and Atacand (candesartan cilexetil). Common drug interactions include disease recurrence among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Apresoline and Atacand. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

What is Atacand?

Atacand has active ingredients of candesartan cilexetil. It is often used in high blood pressure. eHealthMe is studying from 22,473 Atacand users. Check the latest studies of Atacand.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

23 people who take Apresoline and Atacand together, and have interactions are studied.

Apresoline and Atacand drug interactions.

What are the common drug interactions of Apresoline and Atacand, by gender? *:

female:

Disease recurrence
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Electrocardiogram qt prolonged
Family stress
Hyperglycaemia (high blood sugar)
Hypersensitivity
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Procedural haemorrhage (procedural bleeding)
Pulmonary embolism (blockage of the main artery of the lung)

male:

Drug ineffective
Acute stress disorder
Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Confusional state
Depression
Disturbance in attention
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall
Fatigue (feeling of tiredness)

What are the common drug interactions of Apresoline and Atacand, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Social problem
Spinal osteoarthritis (joint cartilage loss in spine)
Spondylitis (an inflammation of the vertebra with spinal cord involvement)
Suicidal ideation
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Acute stress disorder
Adjustment disorder
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Back pain

50-59:

Blood glucose increased
Fatigue (feeling of tiredness)
Pneumonia
Staphylococcal infection (an infection with staphylococcus bacteria)

60+:

Blood pressure diastolic decreased
Lower respiratory tract infection
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood pressure systolic increased
Contusion (a type of hematoma of tissue in which capillaries)
Cystitis (inflammation of the wall of the bladder)
Haemophilus infection (bacterial infection by haemophilus influenzae)
Haemorrhage (bleeding)
Hip fracture
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the existing conditions these people have? *

Asthma: 8 people, 34.78%
Diabetes: 4 people, 17.39%
Pain: 3 people, 13.04%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 8.70%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.70%
Pulmonary Congestion (congestion in the lungs): 2 people, 8.70%
Neuropathy Peripheral (surface nerve damage): 2 people, 8.70%
Nausea And Vomiting: 2 people, 8.70%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Insomnia (sleeplessness): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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