Apresoline and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apresoline (hydralazine hydrochloride) and Lanoxin (digoxin). Common drug interactions include weight increased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Apresoline and Lanoxin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

On Jul, 17, 2026

77 people who take Apresoline and Lanoxin together, and have interactions are studied.

Apresoline and Lanoxin drug interactions.

What are the common drug interactions of Apresoline and Lanoxin, by gender? *:

female:

Weight increased
Acute respiratory failure
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood glucose increased
Cardiomyopathy (weakening of the heart muscle)
Death
Exostosis (formation of new bone on the surface of a bone)
Fluid overload (too much fluid in the blood)
Food intolerance (inability to have food)

male:

Asthenia (weakness)
Pneumonia
Back pain
Bone disorder
Bone pain
Bronchial secretion retention
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiomegaly (increased size of heart than normal)
Cerebral atrophy (decrement in size of brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Apresoline and Lanoxin, by age (0-1 to 60+)? *:

0-1:

Acute respiratory distress syndrome
Pneumonia adenoviral (viral pneumonia caused by an adenovirus)
Respiratory syncytial virus infection (viral disease of respiratory system)

2-9:

Activated partial thromboplastin time prolonged
Antinuclear factor positive
Blood immunoglobulin m increased
Blood urea increased
Faecal occult blood positive
Fibrin d dimer increased
Haemoglobin decreased
Hyperglycaemia (high blood sugar)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypoproteinaemia (too little prolactin circulating in the blood)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood potassium increased
Blood pressure decreased
Bradycardia (abnormally slow heart action)
Cardiac arrest
Dyskinesia (abnormality or impairment of voluntary movement)
Brain hypoxia (reduced supply of oxygen to the brain)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Electrolyte imbalance

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Dyspnoea (difficult or laboured respiration)
Haematoma (collection of blood outside the blood vessels)
International normalised ratio increased
Pancreatitis chronic (chronic inflammation of pancreas)
Pruritus (severe itching of the skin)
Thrombocytopenia (decrease of platelets in blood)
Viral upper respiratory tract infection
Acute respiratory failure
Alcohol abuse

60+:

Pneumonia
Chest pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Pain
Apnoea (suspension of external breathing)
Arthropathy
Back pain
Bone disorder
Bone pain
Bronchial secretion retention

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 17 people, 22.08%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 11.69%
Cardiac Failure: 6 people, 7.79%
Pain: 5 people, 6.49%
Muscle Spasms (muscle contraction): 5 people, 6.49%
Diabetes: 5 people, 6.49%

* Approximation only. Some reports may have incomplete information.

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