Apresoline and Sucralfate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Apresoline (hydralazine hydrochloride) and Sucralfate (sucralfate). Common drug interactions include blood creatinine increased among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Apresoline and Sucralfate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Apresoline?
Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.
What is Sucralfate?
Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.
11 people who take Apresoline and Sucralfate together, and have interactions are studied.

What are the common drug interactions of Apresoline and Sucralfate, by gender? *:
female:
- Blood creatinine increased
- Breast pain
- Cardiac arrest
- Dizziness
- Drug ineffective
- Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
- Fall
- Gait abnormal
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
- Haemoglobin decreased
male:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Anaphylactic reaction (serious allergic reaction)
What are the common drug interactions of Apresoline and Sucralfate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
50-59:
n/a
60+:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
- Fall
- Gait abnormal
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
- Haemoglobin decreased
- Hyperkalaemia (damage to or disease of the kidney)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Injection site bruising
What are the existing conditions these people have? *
- Cardiac Disorder: 4 people, 36.36%
- Pain: 4 people, 36.36%
- Infection: 3 people, 27.27%
- High Blood Cholesterol: 3 people, 27.27%
- Headache (pain in head): 3 people, 27.27%
- Oedema (fluid collection in tissue): 2 people, 18.18%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 18.18%
- Depression: 2 people, 18.18%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
- Urine Output - Decreased: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Apresoline and Sucralfate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Apresoline (2,475 reports)
- Sucralfate (17,548 reports)
Browse all drug interactions of Apresoline and Sucralfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Apresoline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sucralfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Apresoline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sucralfate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydralazine hydrochloride and sucralfate (the active ingredients of Apresoline and Sucralfate, respectively), and Apresoline and Sucralfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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