Apriso and Oxycodone and acetaminophen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Apriso (mesalamine) and Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride). Common drug interactions include confusional state among females and osteopenia among males.
The phase IV clinical study analyzes what interactions people have when they take Apriso and Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Apriso?
Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.
What is Oxycodone and acetaminophen?
Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.
23 people who take Apriso and Oxycodone and acetaminophen together, and have interactions are studied.

What are the common drug interactions of Apriso and Oxycodone And Acetaminophen, by gender? *:
female:
- Confusional state
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Bedridden
- Blood cholesterol increased
- Blood triglycerides increased
- Depression
- Disturbance in attention
- Drug ineffective
- Fatigue (feeling of tiredness)
male:
- Osteopenia (a condition where bone mineral density is lower than normal)
- Emotional distress
- Multiple fractures
- Muscle atrophy (a decrease in the mass of the muscle)
- Quality of life decreased
- Rib fracture
- Dyspnoea (difficult or laboured respiration)
- Parkinson's disease
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
What are the common drug interactions of Apriso and Oxycodone And Acetaminophen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
- Diarrhoea
30-39:
n/a
40-49:
n/a
50-59:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gait disturbance
- Hypertension (high blood pressure)
- Memory impairment
- Pain in extremity
- Weight increased
- Eating disorder
- Heart rate increased
- Hyperhidrosis (abnormally increased sweating)
60+:
- Confusional state
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Chronic kidney disease
What are the existing conditions these people have? *
- Fibromyalgia (a long-term condition which causes pain all over the body): 12 people, 52.17%
- Depression: 11 people, 47.83%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 30.43%
- High Blood Pressure: 7 people, 30.43%
- Post Laminectomy Syndrome: 7 people, 30.43%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 30.43%
- Bacterial Infection: 6 people, 26.09%
- Gout (uric acid crystals building up in the body): 5 people, 21.74%
- Sacroiliitis (an inflammation of the sacroiliac joint): 5 people, 21.74%
- Thyroid Diseases: 5 people, 21.74%
* Approximation only. Some reports may have incomplete information.
Do you take Apriso and Oxycodone and acetaminophen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Apriso (3,439 reports)
- Oxycodone and acetaminophen (14,467 reports)
Browse all drug interactions of Apriso and Oxycodone and acetaminophen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Apriso:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Oxycodone and acetaminophen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Apriso and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxycodone and acetaminophen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mesalamine and acetaminophen; oxycodone hydrochloride (the active ingredients of Apriso and Oxycodone and acetaminophen, respectively), and Apriso and Oxycodone and acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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