Aranesp and Demerol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aranesp (darbepoetin alfa) and Demerol (meperidine hydrochloride). Common drug interactions include nausea among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Aranesp and Demerol. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Aranesp?

Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

On Jul, 11, 2026

65 people who take Aranesp and Demerol together, and have interactions are studied.

What are the common drug interactions of Aranesp and Demerol, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Weight decreased
Anxiety
Anaemia (lack of blood)
Depression
Neck pain
Fatigue (feeling of tiredness)
Injury
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

male:

Anaemia (lack of blood)
Death
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Blood calcium decreased
Blood chloride increased
Blood creatinine increased
Blood pressure decreased

What are the common drug interactions of Aranesp and Demerol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest discomfort
Insomnia (sleeplessness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pleural effusion (water on the lungs)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cholecystitis (infection of gallbladder)
Dyspnoea (difficult or laboured respiration)
Influenza like illness
Lymphadenopathy (disease or enlargement of lymph nodes)

30-39:

Anaemia (lack of blood)
Deformity (disfigurement)
Device related infection
Erythema (redness of the skin)
Hyperkalaemia (damage to or disease of the kidney)
Muscle tightness
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)

40-49:

Back pain
Nausea (feeling of having an urge to vomit)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Anxiety
Deafness
Depression
Injury
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neck pain
Urinary tract infection

50-59:

Cardiac failure congestive
Chest pain
Chills (felling of cold)
Concomitant disease progression (progress in accompanying disease)
Confusional state
Coronary arterial stent insertion
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fatigue (feeling of tiredness)

60+:

Anaemia (lack of blood)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Blood calcium decreased
Blood chloride increased
Blood creatinine increased
Blood pressure decreased
Blood pressure systolic increased

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 13 people, 20.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 13.85%
Oropharyngeal Pain: 6 people, 9.23%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 9.23%
Bone Density Decreased: 5 people, 7.69%
Bone Loss: 4 people, 6.15%

* Approximation only. Some reports may have incomplete information.

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