Aranesp and Feraheme drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aranesp (darbepoetin alfa) and Feraheme (ferumoxytol). Common drug interactions include infection among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Aranesp and Feraheme. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Aranesp?

Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.

What is Feraheme?

Feraheme has active ingredients of ferumoxytol. eHealthMe is studying from 1,884 Feraheme users. Check the latest studies of Feraheme.



On Jul, 12, 2026

30 people who take Aranesp and Feraheme together, and have interactions are studied.

Aranesp and Feraheme drug interactions.

What are the common drug interactions of Aranesp and Feraheme, by gender? *:

female:

  1. Infection
  2. Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
  3. Iron deficiency anaemia
  4. Post procedural haemorrhage (post procedural bleeding)
  5. Pyrexia (fever)
  6. Urine flow decreased
  7. Urine output decreased
  8. Weight increased
  9. Anaphylactic reaction (serious allergic reaction)
  10. Arthralgia (joint pain)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hypotension (abnormally low blood pressure)
  3. Abdominal pain
  4. Diarrhoea
  5. Dizziness
  6. Feeling cold
  7. Haemoglobin decreased
  8. Hyperhidrosis (abnormally increased sweating)
  9. Anxiety
  10. Aortic valve sclerosis (narrowing of the aortic valve)

What are the common drug interactions of Aranesp and Feraheme, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Dyspnoea (difficult or laboured respiration)
  3. Hypertension (high blood pressure)
  4. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  5. Infusion site urticaria (rash of round, red welts on the skin at infusion site)
  6. Pallor

40-49:

  1. Abdominal distension
  2. Catheter site erosion
  3. Catheter site swelling
  4. Generalised oedema (swelling all over the body)
  5. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  6. Infection
  7. Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
  8. Iron deficiency anaemia
  9. Nausea (feeling of having an urge to vomit)
  10. Post procedural haemorrhage (post procedural bleeding)

50-59:

  1. Flushing (the warm, red condition of human skin)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Hypotension (abnormally low blood pressure)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Nausea (feeling of having an urge to vomit)
  6. Oxygen saturation decreased
  7. Pleural effusion (water on the lungs)
  8. Vomiting
  9. Wheezing (a high-pitched whistling sound made while you breath)
  10. Anaphylactic reaction (serious allergic reaction)

60+:

  1. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  2. Anti-erythropoietin antibody positive
  3. Hypotension (abnormally low blood pressure)
  4. Unresponsive to stimuli
  5. Cardiac arrest
  6. Dizziness
  7. Flushing (the warm, red condition of human skin)
  8. Nausea (feeling of having an urge to vomit)
  9. Oxygen saturation decreased
  10. Vomiting

What are the existing conditions these people have? *

  1. Iron Deficiency Anaemia: 7 people, 23.33%
  2. Chronic Renal Failure (kidney failure): 7 people, 23.33%
  3. Iron Deficiency: 5 people, 16.67%
  4. Anaemia (lack of blood): 5 people, 16.67%
  5. Acute Kidney Failure: 5 people, 16.67%
  6. Nephrogenic Anaemia (anaemia due to kidney disease): 3 people, 10.00%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 10.00%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 10.00%
  9. Hyperkalemia (damage to or disease of the kidney): 3 people, 10.00%
  10. Heart Disease: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Aranesp and Feraheme?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aranesp and Feraheme:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aranesp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Feraheme:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aranesp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Feraheme and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on darbepoetin alfa and ferumoxytol (the active ingredients of Aranesp and Feraheme, respectively), and Aranesp and Feraheme (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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