Aranesp and Peginterferon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aranesp (darbepoetin alfa) and Peginterferon (peginterferon alfa-2a; ribavirin). Common drug interactions include haemoglobin decreased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Aranesp and Peginterferon. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Aranesp?

Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.

What is Peginterferon?

Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

40 people who take Aranesp and Peginterferon together, and have interactions are studied.

Aranesp and Peginterferon drug interactions.

What are the common drug interactions of Aranesp and Peginterferon, by gender? *:

female:

Haemoglobin decreased
Dizziness
Alopecia (absence of hair from areas of the body)
Back pain
Cough
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Rash

male:

Anaemia (lack of blood)
Blood creatinine increased
Urinary tract infection
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Thrombocytopenia (decrease of platelets in blood)
Blood urea increased
C-reactive protein increased
Dehydration (dryness resulting from the removal of water)
Glomerular filtration rate decreased

What are the common drug interactions of Aranesp and Peginterferon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiomegaly (increased size of heart than normal)
Carotid artery stenosis (narrowing of carotid artery)
Cellulitis (infection under the skin)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Cerebrovascular disorder (disease of brain)
Confusional state
Cough
Dehydration (dryness resulting from the removal of water)
Delirium (wild excitement)
Diarrhoea

30-39:

Cerebral haemorrhage (bleeding within the brain)

40-49:

Anaemia (lack of blood)
Haemoglobin decreased
Alopecia (absence of hair from areas of the body)
Back pain
Cough
Dizziness
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

50-59:

Chest discomfort
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
White blood cell count decreased
Anaemia (lack of blood)
Cardiac flutter (abnormal heart rhythm)
Cardiomegaly (increased size of heart than normal)
Cerebral vasoconstriction (constriction of brain blood vessels)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)

60+:

Anaemia (lack of blood)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Leukopenia (less number of white blood cells in blood)
Myalgia (muscle pain)
Pruritus (severe itching of the skin)
Thrombocytopenia (decrease of platelets in blood)
Extradural abscess (pus may gather between a patient's skull and his dura)
Sepsis (a severe blood infection that can lead to organ failure and death)
Epistaxis (bleed from the nose)

What are the existing conditions these people have? *

Anaemia (lack of blood): 18 people, 45.00%
Pain: 6 people, 15.00%
High Blood Pressure: 6 people, 15.00%
Depression: 5 people, 12.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 10.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 7.50%
Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 5.00%
Immunodeficiency Disorders: 2 people, 5.00%
Diabetes: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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