Arava and Sular drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arava (leflunomide) and Sular (nisoldipine). Common drug interactions include autoimmune hepatitis among females and subcutaneous abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Arava and Sular. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Sular?

Sular has active ingredients of nisoldipine. It is often used in high blood pressure. eHealthMe is studying from 1,757 Sular users. Check the latest studies of Sular.

On Jul, 19, 2026

12 people who take Arava and Sular together, and have interactions are studied.

What are the common drug interactions of Arava and Sular, by gender? *:

female:

Autoimmune hepatitis
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Fall

male:

Subcutaneous abscess

What are the common drug interactions of Arava and Sular, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Autoimmune hepatitis
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Psoriasis (immune-mediated disease that affects the skin)
Subcutaneous abscess
White blood cell count decreased

60+:

Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Fall
Flushing (the warm, red condition of human skin)
Gastritis (inflammation of stomach)
Hypoxia (low oxygen in tissues)
Post thrombotic syndrome (long-term effects that can occur after venous thrombosis)
Precancerous cells present

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 41.67%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 33.33%
Joint Pain: 4 people, 33.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 33.33%
Micturition Urgency (urgency to pass the urine): 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Cardiac Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and Sular?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously