Aricept and Gliclazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aricept (donepezil hydrochloride) and Gliclazide (gliclazide). Common drug interactions include vomiting among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Aricept and Gliclazide. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Gliclazide?

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.

On Jul, 10, 2026

11 people who take Aricept and Gliclazide together, and have interactions are studied.

Aricept and Gliclazide drug interactions.

What are the common drug interactions of Aricept and Gliclazide, by gender? *:

female:

Vomiting
Fall
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Cerebral haemorrhage (bleeding within the brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Defaecation urgency (a sudden compelling urge to defecate)
Dizziness
Essential hypertension (primary hypertension)
Facial paresis (weakness in facial muscle movement)

male:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Blood creatine phosphokinase increased
Death
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Jaundice cholestatic
Myositis (inflammation of the muscles)

What are the common drug interactions of Aricept and Gliclazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Vomiting
Fall
Hemiparesis (weakness on one side of the body)
Hyperglycaemia (high blood sugar)
Hypertensive crisis
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate adh secretion
Limb asymmetry (consistent task discrepancy between the two lower limbs)
Micturition urgency (urgency to pass the urine)

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 18.18%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 18.18%
Vulvovaginal Dryness: 1 person, 9.09%
Suicide Attempt: 1 person, 9.09%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 9.09%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 9.09%
Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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