Aricept and Mexitil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aricept (donepezil hydrochloride) and Mexitil (mexiletine hydrochloride). Common drug interactions include renal failure among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Aricept and Mexitil. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Mexitil?

Mexitil has active ingredients of mexiletine hydrochloride. eHealthMe is studying from 1,893 Mexitil users. Check the latest studies of Mexitil.

On Jul, 15, 2026

32 people who take Aricept and Mexitil together, and have interactions are studied.

What are the common drug interactions of Aricept and Mexitil, by gender? *:

female:

Renal failure (kidney dysfunction)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Pneumonia
Atrioventricular block complete (heart block complete)
Cardiac arrest
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Electrocardiogram qt prolonged
Hypoglycaemia (deficiency of glucose in the bloodstream)
Syncope (loss of consciousness with an inability to maintain postural tone)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)

male:

Anaemia (lack of blood)
Gaze palsy (disorders affecting the ability to move both eyes in the same direction)
Hemiparesis (weakness on one side of the body)
Renal failure (kidney dysfunction)
Toxic skin eruption (skin breakdown due to toxic substance)
Cerebral haemorrhage (bleeding within the brain)
Diarrhoea
Eye movement disorder
Cardiac failure
Chronic kidney disease

What are the common drug interactions of Aricept and Mexitil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Anaemia (lack of blood)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Ventricular flutter (arrhythmia)
Renal failure (kidney dysfunction)
Abasia (inability to walk)
Faecal incontinence (a lack of control over passing stool)
Platelet count decreased
White blood cell count decreased
Circulatory collapse

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 10 people, 31.25%
Extrasystoles: 5 people, 15.62%
Ventricular Extrasystoles (premature cardiac contraction): 4 people, 12.50%
Dementia (madness): 4 people, 12.50%
Cardiac Failure: 4 people, 12.50%
High Blood Pressure: 2 people, 6.25%
Gastric Ulcer (stomach ulcer): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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