Aricept and Zoledronic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aricept (donepezil hydrochloride) and Zoledronic (zoledronic acid). Common drug interactions include asthenia among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Aricept and Zoledronic. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

On Jul, 12, 2026

17 people who take Aricept and Zoledronic together, and have interactions are studied.

Aricept and Zoledronic drug interactions.

What are the common drug interactions of Aricept and Zoledronic, by gender? *:

female:

Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Depression
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Fall
Gout (uric acid crystals building up in the body)
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
International normalised ratio increased

male:

Fall
Asthenia (weakness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diarrhoea
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Gait disturbance
Haematochezia (passage of stools containing blood)
Hip fracture
Hypotension (abnormally low blood pressure)
Joint swelling

What are the common drug interactions of Aricept and Zoledronic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Fall
Pneumonia
International normalised ratio increased
Lumbar vertebral fracture
Malignant neoplasm progression (cancer tumour came back)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mitral valve stenosis (narrowing of mitral valve)
Normal pressure hydrocephalus (a neurological disorder in which there is too much cerebrospinal fluid in the ventricles of the brain)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Rash

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 47.06%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 11.76%
Osteoporosis (bones weak and more likely to break): 2 people, 11.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.76%
Urinary Tract Infection: 1 person, 5.88%
Upper Respiratory Tract Infection: 1 person, 5.88%
Ph Urine Decreased: 1 person, 5.88%
Pain: 1 person, 5.88%
Nausea (feeling of having an urge to vomit): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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