Aripiprazole and Janumet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aripiprazole (aripiprazole) and Janumet (metformin hydrochloride; sitagliptin phosphate). Common drug interactions include chronic kidney disease among females and sleep disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Aripiprazole and Janumet. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

On Jul, 20, 2026

38 people who take Aripiprazole and Janumet together, and have interactions are studied.

Aripiprazole and Janumet drug interactions.

What are the common drug interactions of Aripiprazole and Janumet, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Uterine cancer
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Herpes zoster
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)

male:

Sleep disorder
Bacteraemia (presence of bacteria in the blood)
Dry eye (lack of adequate tears)
Fall
Gait disturbance
Hospitalisation
Hyperhidrosis (abnormally increased sweating)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Klebsiella infection

What are the common drug interactions of Aripiprazole and Janumet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bacteraemia (presence of bacteria in the blood)
Electrolyte imbalance
Intestinal pseudo-obstruction (syndrome caused by severe impairment in the ability of the intestines to push food through)
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Diarrhoea
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Herpes zoster
Nausea (feeling of having an urge to vomit)
Viral infection
Vomiting
Renal failure (kidney dysfunction)

50-59:

Abdominal pain
Chronic kidney disease
Delusion (a false belief or opinion)
Disease progression
Fall
Gait disturbance
Hepatitis (inflammation of the liver)
Hospitalisation
Klebsiella infection
Myocarditis (inflammation of heart muscle myocardium)

60+:

Uterine cancer
Pulmonary embolism (blockage of the main artery of the lung)
Overdose
Pneumonia
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Insomnia (sleeplessness)
Sleep disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

What are the existing conditions these people have? *

High Blood Cholesterol: 13 people, 34.21%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 31.58%
Cardiac Disorder: 10 people, 26.32%
Pain: 10 people, 26.32%
Infection: 10 people, 26.32%
Stress And Anxiety: 10 people, 26.32%
High Blood Pressure: 9 people, 23.68%
Bipolar Disorder (mood disorder): 8 people, 21.05%
Muscle Spasms (muscle contraction): 8 people, 21.05%
Hypersensitivity: 8 people, 21.05%

* Approximation only. Some reports may have incomplete information.

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