Aripiprazole and Opsumit drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aripiprazole (aripiprazole) and Opsumit (macitentan). Common drug interactions include dyspnoea among females.

The phase IV clinical study analyzes what interactions people have when they take Aripiprazole and Opsumit. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.

What is Opsumit?

Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.

On Jul, 26, 2026

35 people who take Aripiprazole and Opsumit together, and have interactions are studied.

Aripiprazole and Opsumit drug interactions.

What are the common drug interactions of Aripiprazole and Opsumit, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Diarrhoea
Fluid retention (an abnormal accumulation of fluid in the blood)
Pyrexia (fever)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Bacterial infection
Catheter site haemorrhage (bleeding at catheter site)
Contusion (a type of hematoma of tissue in which capillaries)
Device dislocation
Feeling of despair

male:

n/a

What are the common drug interactions of Aripiprazole and Opsumit, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Death
Vomiting
Catheter site discharge
Catheter site infection (infection at the site of insertion)
Colitis ulcerative (inflammation of colon with ulcer)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Rash

30-39:

Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Device related infection

40-49:

Head discomfort
Heart rate increased
Hypertension (high blood pressure)
Immunosuppression
Inflammation
Influenza
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Neuralgia (pain in one or more nerves)
Oedema peripheral (superficial swelling)

50-59:

Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Fall
Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Hypoaesthesia (reduced sense of touch or sensation)
Muscular weakness (muscle weakness)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Paralysis
Asthenia (weakness)

60+:

Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Peripheral swelling
Pneumonia
Polyuria (production of too much dilute urine)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Fall
Femoral neck fracture (neck of femur bone fracture)
Hyperhidrosis (abnormally increased sweating)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 28 people, 80.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 8.57%
Nausea (feeling of having an urge to vomit): 3 people, 8.57%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 5.71%
Nausea And Vomiting: 2 people, 5.71%
Cough: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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