Arixtra and Cytoxan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arixtra (fondaparinux sodium) and Cytoxan (cyclophosphamide). Common drug interactions include back pain among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Arixtra and Cytoxan. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Cytoxan?

Cytoxan has active ingredients of cyclophosphamide. It is often used in breast cancer. eHealthMe is studying from 19,693 Cytoxan users. Check the latest studies of Cytoxan.

On Jul, 10, 2026

17 people who take Arixtra and Cytoxan together, and have interactions are studied.

What are the common drug interactions of Arixtra and Cytoxan, by gender? *:

female:

Back pain
Blood iron increased
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain
Breast cancer recurrent
Cardiac murmur (an heart sound in valve abnormality)
Cardiomegaly (increased size of heart than normal)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

male:

Abdominal discomfort
Diarrhoea
Back pain
Bowel movement irregularity
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Decreased appetite

What are the common drug interactions of Arixtra and Cytoxan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Acute respiratory distress syndrome
Anaemia (lack of blood)
Anxiety
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Application site burn
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Avulsion fracture (bone fracture)

50-59:

Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Erythema (redness of the skin)
Febrile neutropenia (fever with reduced white blood cells)
Memory impairment
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pain

60+:

Abdominal discomfort
Abdominal pain
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Decreased appetite
Dermal cyst
Diarrhoea

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 35.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
Insomnia (sleeplessness): 2 people, 11.76%
Pain: 2 people, 11.76%
Depression: 2 people, 11.76%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 11.76%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 11.76%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 1 person, 5.88%
Anaemia Of Malignant Disease: 1 person, 5.88%
Blood Magnesium Decreased: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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