Arixtra and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arixtra (fondaparinux sodium) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include headache among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Arixtra and Hydroxyzine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

26 people who take Arixtra and Hydroxyzine together, and have interactions are studied.

Arixtra and Hydroxyzine drug interactions.

What are the common drug interactions of Arixtra and Hydroxyzine, by gender? *:

female:

Headache (pain in head)
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Death
Dehydration (dryness resulting from the removal of water)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Renal failure (kidney dysfunction)
Vomiting
Nervous system disorder (a general class of medical conditions affecting the nervous system)

male:

Diarrhoea
Hypokalaemia (low potassium)
Urticaria (rash of round, red welts on the skin that itch intensely)
Angioedema (rapid swelling of the dermis)
Death
Rash
Swelling face
Swollen tongue (swelling of tongue)

What are the common drug interactions of Arixtra and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Chest pain
Headache (pain in head)
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
Death
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Injection site pain
Puncture site pain

50-59:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dehydration (dryness resulting from the removal of water)
Cellulitis (infection under the skin)
Dizziness
Epistaxis (bleed from the nose)
Haemorrhage (bleeding)
Infection
Myelofibrosis (a disease in which abnormal blood cells and fibres build up inside the bone marrow)
Neutropenia (an abnormally low number of neutrophils)
Peripheral swelling

60+:

Diarrhoea
Hypokalaemia (low potassium)
Oedema (fluid collection in tissue)
Rash
Swelling face
Swollen tongue (swelling of tongue)
Thrombocytopenia (decrease of platelets in blood)
Urticaria (rash of round, red welts on the skin that itch intensely)
Angioedema (rapid swelling of the dermis)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 19.23%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 15.38%
Adenocarcinoma Pancreas (cancer of pancreas): 4 people, 15.38%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Arixtra and Hydroxyzine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously