Arixtra and Piperacillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arixtra (fondaparinux sodium) and Piperacillin (piperacillin sodium). Common drug interactions include pulmonary embolism among females and rhabdomyolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Arixtra and Piperacillin. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Piperacillin?

Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.



On Jul, 15, 2026

24 people who take Arixtra and Piperacillin together, and have interactions are studied.

Arixtra and Piperacillin drug interactions.

What are the common drug interactions of Arixtra and Piperacillin, by gender? *:

female:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Septic shock (shock due to blood infection)
  3. Haemoglobin decreased
  4. Melaena (the passage of black, tarry stools)
  5. Rectal haemorrhage (bleeding from anus)
  6. Red blood cell count decreased
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Anaemia (lack of blood)
  9. Bronchial haemorrhage (bleeding in bronchia)
  10. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)

male:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  7. Haematocrit decreased
  8. Heparin-induced thrombocytopenia
  9. Hepatocellular injury (liver injury)
  10. Interstitial lung disease

What are the common drug interactions of Arixtra and Piperacillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
  2. Cough
  3. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  4. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  5. Hepatocellular injury (liver injury)
  6. Interstitial lung disease
  7. Myopericarditis (disease caused by inflammation of the myocardium (muscle of the heart wall) and/or the pericardium)
  8. Pyrexia (fever)
  9. Rash erythematous (redness of the skin)
  10. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

40-49:

n/a

50-59:

n/a

60+:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Anaemia (lack of blood)
  5. Bronchial haemorrhage (bleeding in bronchia)
  6. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  7. C-reactive protein increased
  8. Candiduria (candida in urine)
  9. Cardiovascular disorder (heart diseases)
  10. Citrobacter infection (infection by citrobacter (bacteria))

* Approximation only. Some reports may have incomplete information.

Do you take Arixtra and Piperacillin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Arixtra and Piperacillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arixtra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Piperacillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arixtra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Piperacillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fondaparinux sodium and piperacillin sodium (the active ingredients of Arixtra and Piperacillin, respectively), and Arixtra and Piperacillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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