Arixtra and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arixtra (fondaparinux sodium) and Rocephin (ceftriaxone sodium). Common drug interactions include pyrexia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Arixtra and Rocephin. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 13, 2026

92 people who take Arixtra and Rocephin together, and have interactions are studied.

What are the common drug interactions of Arixtra and Rocephin, by gender? *:

female:

Pyrexia (fever)
Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Abdominal pain lower
Body temperature increased
Chills (felling of cold)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Headache (pain in head)
Hepatic steatosis (fatty liver disease)
Inflammatory marker increased

male:

Abdominal pain
Neutropenia (an abnormally low number of neutrophils)
Hypertension (high blood pressure)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Intestinal obstruction
Device related infection
Abdominal discomfort
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

What are the common drug interactions of Arixtra and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Abdominal distension
Abdominal pain
Intestinal obstruction
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Gamma-glutamyltransferase increased
Hepatocellular damage (liver damage)
Hepatomegaly (abnormal enlargement of the liver)
Pyrexia (fever)

40-49:

Asthenia (weakness)
Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Abdominal pain lower
Arthralgia (joint pain)
Body temperature increased
Chills (felling of cold)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
General physical health deterioration (weak health status)
Headache (pain in head)

50-59:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Peripheral swelling
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Device related infection
Agitation (state of anxiety or nervous excitement)
Oedema peripheral (superficial swelling)
Pain in extremity
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Duodenitis (inflammation of the duodenum)

60+:

Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Hypertension (high blood pressure)
Pain
Renal failure (kidney dysfunction)
Abdominal discomfort
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 17.39%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 11 people, 11.96%
Pain: 10 people, 10.87%
Insomnia (sleeplessness): 6 people, 6.52%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 5.43%

* Approximation only. Some reports may have incomplete information.

Do you take Arixtra and Rocephin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously