Arixtra and Zoledronic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arixtra (fondaparinux sodium) and Zoledronic acid (zoledronic acid). Common drug interactions include vomiting among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Arixtra and Zoledronic acid. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Zoledronic acid?

Zoledronic acid has active ingredients of zoledronic acid. eHealthMe is studying from 28,485 Zoledronic acid users. Check the latest studies of Zoledronic acid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

49 people who take Arixtra and Zoledronic acid together, and have interactions are studied.

Arixtra and Zoledronic acid drug interactions.

What are the common drug interactions of Arixtra and Zoledronic Acid, by gender? *:

female:

Vomiting
Dysphagia (a condition in which swallowing is difficult or painful)
Nausea (feeling of having an urge to vomit)
Pulpitis dental (inflammation of the tooth pulp)
Sensory disturbance (sense disturbance)
Thrombosis (formation of a blood clot inside a blood vessel)
Weight decreased
Hypertension (high blood pressure)
Venous thrombosis limb (blood clot that forms in a vein in the limb)
Interstitial lung disease

male:

Febrile neutropenia (fever with reduced white blood cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Rash erythematous (redness of the skin)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Arixtra and Zoledronic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Interstitial lung disease
Febrile neutropenia (fever with reduced white blood cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Thrombocytopenia (decrease of platelets in blood)

50-59:

Constipation
Oedema peripheral (superficial swelling)
Rash
Skin discolouration (change of skin colour)

60+:

Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Tooth erosion (dissolving teeth)
Vomiting
Weight decreased
Hypertension (high blood pressure)
Venous thrombosis limb (blood clot that forms in a vein in the limb)
Rash erythematous (redness of the skin)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Chest pain

What are the existing conditions these people have? *

Breast Cancer: 24 people, 48.98%
Breast Cancer Metastatic: 22 people, 44.90%
Multiple Myeloma (cancer of the plasma cells): 10 people, 20.41%
Pulmonary Embolism (blockage of the main artery of the lung): 7 people, 14.29%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

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