Armour thyroid and Unithroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Armour thyroid (thyroid tablets, usp) and Unithroid (levothyroxine sodium). Common drug interactions include age-related macular degeneration among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Armour thyroid and Unithroid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Armour thyroid?

Armour thyroid has active ingredients of thyroid tablets, usp. It is often used in hypothyroidism. eHealthMe is studying from 11,975 Armour thyroid users. Check the latest studies of Armour thyroid.

What is Unithroid?

Unithroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 890 Unithroid users. Check the latest studies of Unithroid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

14 people who take Armour thyroid and Unithroid together, and have interactions are studied.

Armour thyroid and Unithroid drug interactions.

What are the common drug interactions of Armour Thyroid and Unithroid, by gender? *:

female:

  1. Age-related macular degeneration
  2. Arthralgia (joint pain)
  3. Chest pain
  4. Drug intolerance (drug sensitivity)
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Muscle tightness
  8. Myalgia (muscle pain)
  9. Nausea (feeling of having an urge to vomit)
  10. Abdominal discomfort

male:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Armour Thyroid and Unithroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Abdominal pain upper
  3. Arthralgia (joint pain)
  4. Back pain
  5. Bone pain
  6. Chest pain
  7. Constipation
  8. Decreased appetite
  9. Diarrhoea
  10. Fatigue (feeling of tiredness)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Arthralgia (joint pain)
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Blood thyroid stimulating hormone increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Burning sensation
  7. Chest discomfort
  8. Dizziness
  9. Drug hypersensitivity
  10. Drug intolerance (drug sensitivity)

60+:

  1. Detachment of retinal pigment epithelium
  2. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  3. Vitreous degeneration (serious vision problems in humans)
  4. Age-related macular degeneration
  5. Drug hypersensitivity
  6. Drug intolerance (drug sensitivity)
  7. Dyspnoea exertional (breathlessness or shortness of breath)
  8. Muscle tightness
  9. Neuromyopathy (disease of both muscles and nerves)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 3 people, 21.43%
  2. Osteoporosis (bones weak and more likely to break): 3 people, 21.43%
  3. Cystitis Interstitial (unknown cause characterized by bladder pain): 3 people, 21.43%
  4. Abdominal Discomfort: 3 people, 21.43%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
  6. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 14.29%
  7. Weight Loss: 1 person, 7.14%
  8. Pain: 1 person, 7.14%
  9. High Blood Pressure: 1 person, 7.14%
  10. High Blood Cholesterol: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Armour thyroid and Unithroid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Armour thyroid and Unithroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Armour thyroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Unithroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Armour thyroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Unithroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on thyroid tablets, usp and levothyroxine sodium (the active ingredients of Armour thyroid and Unithroid, respectively), and Armour thyroid and Unithroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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