Arthrotec and Claritin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arthrotec (diclofenac sodium; misoprostol) and Claritin (loratadine). Common drug interactions include fatigue among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Arthrotec and Claritin. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.



On Jul, 12, 2026

89 people who take Arthrotec and Claritin together, and have interactions are studied.

Arthrotec and Claritin drug interactions.

What are the common drug interactions of Arthrotec and Claritin, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Urinary tract infection
  4. Arthralgia (joint pain)
  5. Dyspnoea (difficult or laboured respiration)
  6. Hypertension (high blood pressure)
  7. Weight increased
  8. Anxiety
  9. Dizziness
  10. Faecal incontinence (a lack of control over passing stool)

male:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Chronic kidney disease
  3. Dizziness
  4. Drug ineffective
  5. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  6. Fatigue (feeling of tiredness)
  7. Gastritis (inflammation of stomach)
  8. Haematemesis (vomiting of blood)
  9. Headache (pain in head)
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Arthrotec and Claritin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Abdominal pain upper
  2. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  3. Tardive dyskinesia (a disorder that involves involuntary movements)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Pain in extremity
  3. Dermatitis psoriasiform (large white or silver flakes on the skin)
  4. Dyspnoea (difficult or laboured respiration)
  5. Panic attack
  6. Urinary tract infection
  7. Drug ineffective
  8. Fatigue (feeling of tiredness)
  9. Hepatic enzyme increased
  10. Psoriasis (immune-mediated disease that affects the skin)

50-59:

  1. Anxiety
  2. Blood amylase increased
  3. Blood bilirubin increased
  4. Blood potassium decreased
  5. Blood sodium decreased
  6. Haematemesis (vomiting of blood)
  7. Headache (pain in head)
  8. Platelet count decreased
  9. Actinic keratosis (skin disease due to sun exposure)
  10. Alopecia (absence of hair from areas of the body)

60+:

  1. Abdominal pain
  2. Blood creatinine increased
  3. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Insomnia (sleeplessness)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Urinary tract infection
  8. Alopecia areata (patchy baldness that typically begins with rapid hair loss)
  9. Anal fissure
  10. Back pain

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 21 people, 23.60%
  2. Pain: 9 people, 10.11%
  3. High Blood Pressure: 8 people, 8.99%
  4. Hypersensitivity: 6 people, 6.74%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.74%
  6. Depression: 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

Do you take Arthrotec and Claritin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Arthrotec and Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arthrotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Claritin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium; misoprostol and loratadine (the active ingredients of Arthrotec and Claritin, respectively), and Arthrotec and Claritin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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