Asa and Pentasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asa (aspirin) and Pentasa (mesalamine). Common drug interactions include presyncope among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Asa and Pentasa. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,326 Pentasa users. Check the latest studies of Pentasa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

93 people who take Asa and Pentasa together, and have interactions are studied.

What are the common drug interactions of Asa and Pentasa, by gender? *:

female:

Presyncope
Spinal fracture (fracture in one of vertebrae)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight decreased
Postmenopausal haemorrhage (post-menopausal bleeding)
Abdominal pain upper
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anal haemorrhage
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

Pneumonia
Arthralgia (joint pain)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Sinusitis (inflammation of sinus)
Skin cancer
Abdominal pain
Balance disorder
Blood pressure fluctuation

What are the common drug interactions of Asa and Pentasa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anal haemorrhage
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dizziness
Dyspnoea (difficult or laboured respiration)
Enteritis (inflammation of the small intestine)
Hyperhidrosis (abnormally increased sweating)
Nausea (feeling of having an urge to vomit)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Chills (felling of cold)
Cough
Dry mouth
Feeling cold
Gout (uric acid crystals building up in the body)
Headache (pain in head)
Heart rate irregular
Influenza
Injection site bruising
Insomnia (sleeplessness)

60+:

Arthralgia (joint pain)
Abdominal pain
Skin cancer
Asthenia (weakness)
Balance disorder
Haematochezia (passage of stools containing blood)
Insomnia (sleeplessness)
Knee deformity (functional disability of knee)
Palpitations (feelings or sensations that your heart is pounding or racing)
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 31 people, 33.33%
High Blood Cholesterol: 16 people, 17.20%
Gout (uric acid crystals building up in the body): 11 people, 11.83%
High Blood Pressure: 9 people, 9.68%
Depression: 8 people, 8.60%
Pain: 7 people, 7.53%
Back Pain: 7 people, 7.53%
Asthma: 7 people, 7.53%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 5.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

Do you take Asa and Pentasa?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously