Asa and Zelboraf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asa (aspirin) and Zelboraf (vemurafenib). Common drug interactions include alanine aminotransferase increased among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Asa and Zelboraf. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

What is Zelboraf?

Zelboraf has active ingredients of vemurafenib. eHealthMe is studying from 8,392 Zelboraf users. Check the latest studies of Zelboraf.



On Jul, 16, 2026

13 people who take Asa and Zelboraf together, and have interactions are studied.

Asa and Zelboraf drug interactions.

What are the common drug interactions of Asa and Zelboraf, by gender? *:

female:

  1. Alanine aminotransferase increased
  2. Arthralgia (joint pain)
  3. Aspartate aminotransferase increased
  4. Decreased appetite
  5. Dyspnoea (difficult or laboured respiration)
  6. Electrocardiogram qt prolonged
  7. Fatigue (feeling of tiredness)
  8. Squamous cell carcinoma (a cancer of a kind of epithelial cell)

male:

  1. Arthralgia (joint pain)
  2. Rash
  3. Pain
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Weight decreased
  6. Weight increased
  7. Nausea (feeling of having an urge to vomit)
  8. Pruritus (severe itching of the skin)
  9. Sunburn
  10. Mass

What are the common drug interactions of Asa and Zelboraf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Haemoglobin decreased
  2. Rash

50-59:

n/a

60+:

  1. Arthralgia (joint pain)
  2. Fatigue (feeling of tiredness)
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  4. Weight decreased
  5. Weight increased
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nausea (feeling of having an urge to vomit)
  8. Asthenia (weakness)
  9. Blood pressure diastolic decreased
  10. Body temperature decreased

What are the existing conditions these people have? *

  1. Malignant Melanoma (skin cancer rises from melancytes): 9 people, 69.23%
  2. High Blood Pressure: 5 people, 38.46%
  3. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 15.38%
  4. Thyroid Diseases: 1 person, 7.69%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  6. Pain: 1 person, 7.69%
  7. Metastatic Neoplasm (spreadable cancer tumour): 1 person, 7.69%
  8. Lymphoma (cancer that begins in immune system cells): 1 person, 7.69%
  9. Hairy Cell Leukaemia (a type of blood cancer): 1 person, 7.69%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Asa and Zelboraf?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Asa and Zelboraf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Asa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zelboraf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Asa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zelboraf and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aspirin and vemurafenib (the active ingredients of Asa and Zelboraf, respectively), and Asa and Zelboraf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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