Asacol and Altace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Asacol (mesalamine) and Altace (ramipril). Common drug interactions include pruritus among females and oedema peripheral among males.
The phase IV clinical study analyzes what interactions people have when they take Asacol and Altace. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Asacol?
Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.
What is Altace?
Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,681 Altace users. Check the latest studies of Altace.
52 people who take Asacol and Altace together, and have interactions are studied.

What are the common drug interactions of Asacol and Altace, by gender? *:
female:
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
- Skin burning sensation
- Swelling face
- Abdominal pain upper
- Cough
- Erythema (redness of the skin)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Pneumonia
- Weight decreased
male:
- Oedema peripheral (superficial swelling)
- Drug ineffective
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Asthenia (weakness)
- Blood alkaline phosphatase decreased
- Blood creatine phosphokinase increased
- Chest pain
- Confusional state
- Cough
What are the common drug interactions of Asacol and Altace, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
40-49:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Chest pain
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Disturbance in attention
- Dyspnoea exertional (breathlessness or shortness of breath)
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Oedema peripheral (superficial swelling)
- Drug ineffective
- Injection site pain
50-59:
- Asthenia (weakness)
- Asthma
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Coma (state of unconsciousness lasting more than six hours)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Device failure
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Eye haemorrhage (bleeding in the eye)
- Feeling jittery
60+:
- Chills (felling of cold)
- Dizziness
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood alkaline phosphatase decreased
- Blood creatine phosphokinase increased
- Confusional state
- Depression
- Diarrhoea
What are the existing conditions these people have? *
- High Blood Cholesterol: 10 people, 19.23%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 13.46%
- Back Pain: 5 people, 9.62%
- Pain: 4 people, 7.69%
- Diabetes: 4 people, 7.69%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 7.69%
- Type 2 Diabetes: 3 people, 5.77%
- Migraine (headache): 3 people, 5.77%
- Inflammatory Bowel Disease: 3 people, 5.77%
- Erection Problems: 3 people, 5.77%
* Approximation only. Some reports may have incomplete information.
Do you take Asacol and Altace?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Asacol and Altace:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Altace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Asacol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Altace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mesalamine and ramipril (the active ingredients of Asacol and Altace, respectively), and Asacol and Altace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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