Asacol and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asacol (mesalamine) and Cyclophosphamide (cyclophosphamide). Common drug interactions include adenomatous polyposis coli among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Asacol and Cyclophosphamide. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.



On Jul, 17, 2026

39 people who take Asacol and Cyclophosphamide together, and have interactions are studied.

Asacol and Cyclophosphamide drug interactions.

What are the common drug interactions of Asacol and Cyclophosphamide, by gender? *:

female:

  1. Adenomatous polyposis coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine)
  2. Alopecia (absence of hair from areas of the body)
  3. Anaemia (lack of blood)
  4. Antiphospholipid antibodies positive
  5. Anxiety
  6. Aortic valve sclerosis (narrowing of the aortic valve)
  7. Asthenia (weakness)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Blood alkaline phosphatase increased
  10. Blood cholesterol increased

male:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Faeces hard
  4. Gastrointestinal pain
  5. Headache (pain in head)
  6. Intestinal obstruction
  7. Markedly reduced food intake
  8. Muscle spasms (muscle contraction)
  9. Pain
  10. Pyrexia (fever)

What are the common drug interactions of Asacol and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Abdominal pain
  3. Colitis pseudomembranous (antibiotic-associated diarrhoea)
  4. Vomiting
  5. Diarrhoea
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Intestinal obstruction
  9. Markedly reduced food intake
  10. Neutropenia (an abnormally low number of neutrophils)

40-49:

  1. Hypovolaemic shock (shock caused by severe blood or fluid loss)
  2. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  3. Arthralgia (joint pain)
  4. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  5. Joint swelling

50-59:

  1. Hypovolaemia (a decreased volume of circulating blood in the body)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Sudden death
  4. Blood alkaline phosphatase increased
  5. Dehydration (dryness resulting from the removal of water)
  6. Diarrhoea
  7. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  8. Fall
  9. Headache (pain in head)
  10. Hepatic cyst

60+:

  1. Diarrhoea
  2. Dizziness
  3. Fatigue (feeling of tiredness)
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Gastrointestinal pain
  6. Pain
  7. Bone marrow failure
  8. Depression
  9. Dyspnoea (difficult or laboured respiration)
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 20.51%
  2. Breast Cancer: 7 people, 17.95%
  3. Depression: 7 people, 17.95%
  4. High Blood Cholesterol: 7 people, 17.95%
  5. Stress And Anxiety: 6 people, 15.38%
  6. High Blood Pressure: 6 people, 15.38%
  7. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 12.82%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 10.26%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 10.26%
  10. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Asacol and Cyclophosphamide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Asacol and Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Asacol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Asacol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and cyclophosphamide (the active ingredients of Asacol and Cyclophosphamide, respectively), and Asacol and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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