Asacol and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asacol (mesalamine) and Senna (senna). Common drug interactions include blood pressure fluctuation among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Asacol and Senna. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 13, 2026

22 people who take Asacol and Senna together, and have interactions are studied.

What are the common drug interactions of Asacol and Senna, by gender? *:

female:

Blood pressure fluctuation
Chronic kidney disease
Death
Heart rate irregular
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertension (high blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Arthralgia (joint pain)
Dysphonia (speech disorder attributable to a disorder of phonation)

male:

Altered state of consciousness (altered state of mind)
Chest discomfort
Pain in extremity
Pain of skin
Poor venous access
Pyrexia (fever)
Rash
Rash erythematous (redness of the skin)
Skin disorder (skin disease)
Skin swelling

What are the common drug interactions of Asacol and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chest discomfort
Chest pain
Hypertension (high blood pressure)
Infusion site bruising
Infusion site discolouration
Infusion site pain
Pain in extremity
Pain of skin
Poor venous access
Pyrexia (fever)

50-59:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Asthenia (weakness)
Blood pressure increased
Cardiac arrest
Device occlusion
Dyspnoea (difficult or laboured respiration)
Electrolyte imbalance

60+:

Altered state of consciousness (altered state of mind)
Haemorrhage subcutaneous (bleeding from skin)
Arthralgia (joint pain)
Chronic kidney disease
Fatigue (feeling of tiredness)
Femur fracture
Groin pain
Haemoglobin decreased
Hallucination (an experience involving the perception of something not present)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 31.82%
Pain: 6 people, 27.27%
Type 2 Diabetes: 3 people, 13.64%
Chronic Kidney Disease: 3 people, 13.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 13.64%
Heart Attack: 3 people, 13.64%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 13.64%
Insomnia (sleeplessness): 3 people, 13.64%
Itching: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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